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《Neural Injury and Functional Reconstruction》 2014-06
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Efficacy of Computer aided Training combined with Hyperbaric Oxygen Therapy on Stroke Patients with Cognitive Dysfunction

LU Min;LOU Wei-wei;XIAO Lu;Department of Rehabilitation Medicine, Tongji Medical College, Huazhong University of Science and Technology;  
Objective: To explore the clinical effects of computer aided training combined with hyperbaric oxygen therapy(HBOT) on stroke patients with cognitive dysfunction. Methods: Sixty stroke patients with cognitive dysfunction were randomly assigned to groups of control, HBOT and combined treatment, with 20 cases in each group. The 3 groups were treated with basic medication and traditional rehabilitation therapy while HBOT group was treated additionally with HBOT and combined treatment group was treated additionally with HBOT and computer aided training. Montreal Cognitive Assessment(Mo CA), Fugl-meyer Scale(FMA) and Barthel Index(BI)were assessed at pre-therapy and 4 weeks after treatment. Results: The scores of Mo CA, FMA and BI in HBOT group and combined treatment group after treatment were much higher than those of control group(P0.05), while the scores of Mo CA and BI in combined treatment group demonstrated much higher than those of HBOT group(P0.05). However, there was no significant difference of FMA scores between 2 groups after treatment. The correlation between sub-items of Mo CA and FMA, BI were analyzed. There were significant correlations between FMA scores and five sub-items(VS-EF, MEM, ATT, ABS, D-MEM) scores of Mo CA(r=0.324~0.521,P0.05 or 0.01). Significant correlations between BI scores and seven sub-items(VS-EF, NAM, MEM, ATT, ABS, D-MEM,ORI) scores of Mo CA(r=0.342~0.537,P0.05 or 0.01) were also shown. Conclusion: Computer aided training combined with HBOT can effectively improve cognitive function of stroke patients.
【CateGory Index】: R743.3;R749.13
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