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《Neural Injury and Functional Reconstruction》 2014-06
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Electrophysiology and Clinical Features of Neuromyotonia

CHEN Bo;WANG Qiong;KE Gao-tan;BU Bi-tao;Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology;  
Objective: To investigate the characteristics of neuromyotonia in clinical manifestation, electromyographic features and treatment. Methods: The clinical manifestation, electromyographic features and treatment of four neuromyotonia cases were analyzed. Results: The four patients manifested muscle twitching at rest and EMG revealed spontaneous, continuous, irregularly occurring multiple motor unit discharges, firing at high frequency.Three out of the four patients were not cured by anti-epilepsy drugs such as Carbamazepine or Phenytoin before prednisone was added. Conclusion: The symptoms of acquired neuromyotonia can be alleviated by Carbamazepine or Phenytoin. The remarkable effect may be achieved by prednisone. The data supports the evidence that the acquired neuromyotonia is a disorders of mediated by autoimmunity.
【CateGory Index】: R746;R741.044
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