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《Neural Injury and Functional Reconstruction》 2014-06
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A Randomized Clinical Trial on Antianxiety and Antidepression Effects of Seniovita

GAO Bo-ting;JIANG Ya-ping;XU Jin-zhi;HU Xiao-qing;WEI Yin-xiu;YANG Yuan;Department of Neurology,Tongji Hospital, Tongji Medical College, Huazhong University of Science an Technology;  
Objective: To evaluate the efficacy and safety of Seniovita coated tablets in the treatment of the patients with mild and moderate anxiety and/or depression.Methods: A total of 322 patients with mild and moderate anxiety and/or depression were randomly divided into Seniovita group(n=162) and control group(n=160).The Seniovita group was orally given Seniovita(2 tablets, tid), and the controlled group was orally given Deanxit(1 tablet, bid). The efficacy of the 2 groups were evaluated with Hamilton Anxiety Scale(HAMA) and Hamilton Depression Scale(HAMD) before and 2, 4, 6, 8 week after the treatment. Results: There was a significant decline in HAMA score and HAMD score in the 2 groups at 2nd week after treatment(P0.05). There was no significant difference between the 2 groups in HAMA score and HAMD after the treatment(P0.05). At 8th week after the treatment, there was no significant difference between the 2 groups in the obvious effective rate and the curative rate. Conclusion: Seniovita coated tablet is safe and effective in treating anxiety and depression.
【CateGory Index】: R749.4;R749.72
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