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《Neural Injury and Functional Reconstruction》 2014-06
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Clinical Effect of Paroxetine Combined with Baimai Recipe on the Treatment of Patients with Chronic Tension-type Headache

ZHOU Hao;XU Lei;WANG Nuan;HUANG Hong-li;Department of Neurology, the First People's Hospital of Xuzhou;  
Objective: To observe the clinical effect of Paroxetine combined with baimai recipe on the treatment of chronic tension-type headache(CTH). Methods: Sixty CTH patients were randomly divided into observation group treated with Paroxetine combined with baimai recipe and control group treated with Paroxetine combined with placebo recipe(n=30) with the course of treatment of 8 weeks. The second latency(ESP2), time limit, electromyogram frequency and amplitude variation of exteroceptive suppression experiment(ESP) in patients before and after treatment were measured. The emotion and quality of life of headache severity, anxiety and depression were evaluated. Results: The patients in the two groups presented significantly decreased EPS2 latency and prolonged time limit after treatment compared with those before treatment(P0.05). The electromyogram frequency and amplitude had no obvious change in control group, which showed obvious reduction in observation group. The headache degree and anxiety and depression score was significantly lower and the quality of life score was significantly higher than those before treatment(P0.05). After the treatment, the ESP2 latency and time limit in the observation group were shorter than the control group(P0.05). The headache degree and anxiety and depression score was significantly lower in the observation group than that of the control group(P0.05). The quality of life score was significantly higher in the observation group than that in the control group(P0.05). Conclusion: The clinical effect of Paroxetine combined with baimai was better than that using a single Paroxetine in the treatment of CTH.
【CateGory Index】: R741
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