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《Neural Injury and Functional Reconstruction》 2014-06
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Dexmedetomidine Anaesthesia for Stereotactic Hematoma Aspiration in Treating Cerebral Hemorrhage

KUAI Jian-ke;YU Dai-hua;GAO Chang-jun;WANG Bin-rong;SUN Xu-de;Department of Anesthesiology, Tangdu Hospital of The Fourth Military Medicine Hospital;  
Objective: To investigate the effect of dexmedetomidine anaesthesia on stereoscopic hematoma aspiration in treating cerebral hemorrhage. Methods: Sixty-nine patients with hypertensive cerebral hemorrhage were randomly divided into the observation group of 34 cases and the control group with 35 cases. All the patients were initially injected with 1 μg/kg of Fentanyl before preoperative anesthesia. The control group was treated with routine anesthesia methods. The observation group was anaesthetized with dexmedetomidine. The mean arterial blood pressure(MAP), PaO2, PaCO2 in the patients in operating room(T1), propofol and dexmedetomidine(T2), after placement of head frame(T3), after drilling(T4), were recorded. The adverse reactions of the two groups were compared. Results: In the observation group, the heart rate in the T3 and T4time group was significantly decreased compared with the control group whereas the PaO2 in the T3 and T4 time group was significantly increased compared with the control group(P0.05). Compared with the control group, the MAP, PaCO2 in T4 time of the observation group showed significant changes(P0.05). The hypotension, tachycardia, impetuous people, postoperative vomiting numbers in the observation group changed significantly compared with the control group(P0.05). Conclusion:Compared with propofol, dexmedetomidine showed a better effect on anesthesia for the treatment of cerebral hemorrhageusing stereotactically minimal invasive suction of intracranial hematomas. The patients showed more stable MAP, heart rate, PaO2 wave, and less respiratory depression.
【CateGory Index】: R614
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