Changes of CVR capacity and its Related Factors in Patients with Symptomatic MCA Ischemia
HUANG Zhong-wei;CHEN Gang;NI Hai-xin;Department of Neurology,People's Hospital of Haimen City;
Objective: To observe the changes of cerebral vascular reserve(CVR) capacity in patients with symptomatic middle cerebral artery(MCA) ischemia and analyze the related factors. Methods: Total 50 patients with symptomatic MCA ischemia were enrolled as observation group, and 50 healthy adults were enrolled as control group. The difference in CVR between the two groups were compared. The difference in CVR capacity of MCA patients with different clinical pathological features were further analyzed. The factors affecting CVR capacity in patients with MCA were analyzed. Results: The CVR of the patients in the observation group was significantly lower than that in the control group(t=6.276, P0.001). Symptomatic MCA patients with age≥65years, hypertension, hyperlipidemia, smoking and presented lower CVR. Multivariate analysis showed that the combination of hyperlipidemia, hypertension and smoking were the factors influencing CVR capacity. Conclusion: Patients with symptomatic MCA ischemia have obvious lower CVR, which were strongly associated with hyperlipidemia, hypertension, and smoking.