Clinical Efficacy of Oxiracetam on Cognitive Impairment of Cerebral Infarction Patients
GONG Xue-qin;YANG Chao;BI Juan;LI Heng;HU Ji-chuan;Department of Neurology,Dongxihu District People's Hospital in Wuhan City;
Objective: To explore clinical effect and safety of oxiracetam on cognitive impairment of cerebral infarction patients. Methods: Total 100 cerebral infarction patients with cognitive impairment were randomly divided into groups of control and Oxiracetam with 50 cases in each group. The two groups were given routine treatment, and the Oxiracetam group was added oxiracetam treatment. Scores of MMSE, ADL and clinical effects were compared between the two groups after treatment. Results: After treatment, the patients in the Oxiracetam group showed a significant higher MMSE score and lower ADL score than those in the control group(P0.05). The total effective rate of the Oxiracetam group was 92.0%, obviously higher than that in the control group(74.0%, P0.05). Conclusion:Oxiracetam is effective and safe to attenuate cognitive impairment of cerebral infarction patients.