Efficacy and Safety of Aneurysm Embolization Combined with Cerebrospinal Fluid Replacement for Subarachnoid Hemorrhage Caused by Aneurysm
WANG Bai-xin;WANG Guang-lv;Depart-ment of Neurosurgery,The People's Hospital of Guangxi Zhuang Autonomous Region;
Objective: To explore and analyze the efficacy and safety of aneurysm embolization combined with cerebrospinal fluid replacement for subarachnoid hemorrhage(SAH) caused by aneurysm. Methods: Ninety-six cases of SAH caused by aneurysm were randomly divided into control group and observation group(n=48 respectively).The cases in the control group were treated with interventional embolization, while the cases in the observation group were given cerebrospinal fluid replacement combined with interventional embolization. The efficacy, the time duration of headache, cerebrospinal fluid returning to normal, neck stiffness, hospital stay, complications and mortality rate were compared between the 2 groups. Results: The total effective rate of the control group was 62.50%, significantly lower than that of the observation group 89.58%(P0.05). The time duration of headache, cerebrospinal fluid return to normal, neck stiffness, hospital stay of the observation group were shorter than those of the control group(P0.05). The rate of cerebral vasospasm and hydrocephalus in the operation group were significantly lower than those in the control group(P0.05). There were no statistically differences in mortality and rebleeding rate between the 2 groups(P0.05). Conclusion: It is an effective and safe way to treat SAH caused by aneurysm with aneurysm embolization combined with cerebrospinal fluid replacement.