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《Foreign Medical Sciences Section On Neurology & Neurosurgery》 2005-04
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Clinical analysis of 198 cases of myasthenia gravis patients with thymectomy

LIU Hong-Bin, YANG Guang-Wei, LIANG Qing-Cheng. Department of Neurology, Third Affiliated Hospital, Qiqihaer Medical College, Qiqihaer, Heilongjiang 161000, China  
Objective To study the relationship between pathological changes of thymus gland and clinical features in patients with myasthenia gravis. Methods The medical data from 198 cases of myasthenia gravis patients, who underwent thymectomy between January, 1990 and January, 2005 were studied retrospectively. Results Among the 198 cases of myasthenia gravis, 158 were accompanied with thymus gland hyperplasia, and 34 with thymus gland lump. The Osserman typing in the former was predominantly presented with type Ⅰand type Ⅱ, while the latter predominantly presented with type Ⅱa and type Ⅱb. The clinical characteristics of the two group patients were different. The age, disease course, pathologic changes and clinical type of thymus gland were impact factors for operation effects. Conclusions The clinical features of myasthenia gravis may be associated with the pathological changes of thymus gland. The influence of the curative effect of thymectomy for myasthenia gravis is multifactorial.
【CateGory Index】: R746
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