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《International Journal of Laboratory Medicine》 2008-02
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The distribution and drug resistance analysis of pathogenic bacteria isolated from blood samples during the last three years

WEN Qing-hui,GUO Zhi-qin,LI Feng-ying,et al.Department of Clinical Laboratory, Dongguan People Hospital,Dongguan 523018,China  
Objective To investigate the distribution and drug resistance situation of pathogenic bacteria isolated from blood samples.Methods Blood culture samples were analyzed with Bact/Alert 3D automated hcmanalysis system and pathogenic bacteria were identified with ATB Expression identification analyzer. Kirby-Bauer disk diffusion method was employed to perform drug sensistivity test.Results A total of 189 (7.3%)strains of bacteria were isolated from 2 593 cases of blood samples.The detected strains(%)of gram negative bacilli and gram positive cocci were 100(52.91%)and 80(42.34%)respectively.The six most common isolated bacteia were Escherichia coli(26.46%),Staphylococcus epidermidis(14.29%), Klebsiella pneumoniae(13.23%),Staphylococcus haemlytieus(11.11%),Staphylococcus aures(6.35%) and Pseudomonas aeruginosa(6.35%)respectively.Drug sensitivity test showed that gram negative bacilli were more sensitive to imipenem and meropenem,while gram positive cocci were more sensitive to vancomycin, nitrofurantoin and teicoplanin.Conclusion Escherichia coli,Klebsiella pneumoniae and Staphylococci were dominant pathogenic bacteria in blood culture samples.The drug resistance statue of isolated strains is serious.It suggests that antibiotics he used rationally so as to enhance clinical therapeutic efficacy.
【CateGory Index】: R446.5
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