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Study on the drug resistance of 45 hacemophilus par lainfluenzae in respiratory tract infection

LI Yun (Department of Clinical Laboratory,Kunming General Hospital of PLA,Yunnan 650032,China)  
Objective To investigate the infectious state and drug resistance of Haemophilus par lainfluenzae in respiratory tract infection,so as to instruct the rational use of antibiotics.Methods Haemophilus par lainfluenzae were isolated from the patients with respiratory tract infection and performed by K-B methods.Nitrocefin slip test was applied into detectingβ-lactamase.Results A total of 45 Haemophilus par lainfluenzae were isolated from 760 specimen,with the isolation rate being 5.92%.Amoxicillin /claulanic acid,Azithromycin,Imipenem,Ceftazidime and Cefuroxime had the better antibiotic function and the average drug resistance was lower than 5%,Theβ-lactamase positive rate was 37.78%.Conclusion The high drug resistance andβ-lactamase positive rate of Haemophilus par lainfluenzae isolated from respiratory tract characterized by multi-resistance must be taken seriousely.
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