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《International Journal of Laboratory Medicine》 2015-01
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Measurement and clinical significance of D-dimer during perioperative period in advanced age patients with hip fracture

Lu Yan;Cai Pan;Tang Mingrong;Dai Jun;Wang Yan;Department of Clinical Laboratory,Zhoupu Hospital of Pudong New Area;Department of Orthopedics,Zhoupu Hospital of Pudong New Area;  
Objective To investigate the change and clinical significance of blood D-dimer level during perioperative period in advanced age hip fracture.Methods The blood D-dimer level in 60 patients aged over 80 years old with hip fracture was detected before operation and after operation,which including at admission(T1),immediately preoperation(T2),immediately postoperation(T3)and on postoperative 1d(T4).Results The positive rates of D-dimer at T1,T2,T3 and T4 were 6.67%,16.45%,41.67%and 80.00% respectively;there were statistically significant differences between T3,T4 and T1,T2,between T3 and T4(P0.05);there was no statistically significant difference between T1 and T2(P0.05).Conclusion The level of D-dimer in advanced age hip fracture has significant change before and after operation.The change of the D-dimer positive rate is an effective index for preventing lower limbs deep venous thrombosis and has the important clinical significance to dynamically monitor the D-dimer level during perioperative period in advanced age hip fracture.
【Fund】: 上海市医学重点专科基金资助项目(ZK2012B03)
【CateGory Index】: R687.3;R446.1
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