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《International Journal of Laboratory Medicine》 2015-01
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Analysis on correlation between multiple biochemical indicators and T2DM complicating gout

Huang Aixia;Department of Clinical Laboratory,Jianli County People′s Hospital;  
Objective To explore the correlation between the levels of uric acid(UA),plasma total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),lipoprotein A(LPL)and hypersensitive C-reactive protein(hs-CRP)with type 2diabetes mellitus(T2DM)complicating gout.Methods The levels of UA,TC,TG,HDL-C,LDL-C,LPL and hs-CRP in the T2 DM complicating gout group,the T2 DM without gout group and the gout group were measured and statistically analyzed to evaluate whether the differences of these indicators among 3groups having statistical significance.Results Compared with the T2 DM without gout group,the TG,LDL-C,hs-CRP and UA levels in the T2 DM complicating gout were increased(P0.05),while the HDL-C level was decreased(P0.05).Ccompared with the gout group,the GLU,TG,LDL-C,LPL,hs-CRP and UA levels in the T2 DM complicating gout group were significantly increased(P0.05)and the HDL-C level was decreased(P0.05).The UA level in the T2 DM complicating gout group was positively correlated with GLU,TC,TG,LDL-C,LPL and hs-CRP levels(P0.05),the correlation coefficient were 0.313,0.283,0.422,0.297 and 0.436 respectively,which was negatively correlated with HDL-C(P0.05),the correlation coefficient was-0.523.Conclusion The UA,TC,TG,HDL-C,LDL-C,LPL and hs-CRP levels have close correlation with T2 DM complicating gout,detecting these biochemical indicators is helpful to monitor and control the occurrence and the development of T2 DM complicating gout.
【CateGory Index】: R587.1;R589.7;R446.1
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