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《International Journal of Laboratory Medicine》 2015-02
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Analysis of clinical distribution and drug susceptibility results of hospital infection of Staphylococcus aureus

Ma Ling;Ye Yang;Zhang Fang;Department of Clinical Laboratory,Changji Prefecture People′s Hospital in Xinjiang Uygur Autonomous Region;  
Objective To explore the clinical distribution and drug resistance of Staphylococcus aureus(SAU),provide a scientific basis for clinical rational use of antibacterial drugs.Methods VITEK-2bacterial identification and drug susceptibility system were used to do the identification and drug sensitive test in the SAU isolated from the secretions,sputum,blood and other kinds of specimen in Changji Prefecture People′s Hospital in Xinjiang Uygur Autonomous Region from January 2011 to April 2014.The results were analyzed by the software WHONET5.5and SPSS17.0.Results A total of 315 strains SAU were isolated,including 64 strains of methicillin-resistant Staphylococcus aureus(MRSA),with the detection rate 20.3%.The most clinical specimens were secretions specimens accounted for 53.7%,followed by sputum specimens accounted for 15.2%.The most specimens were from department of orthopaedic and dermatology,accounted for 26.0% respectively,followed by the department of kidney disease accounted for 14.0%.Except for erythromycin,vancomycin,tigecycline and rina amine,the antimicrobial resistance rates of MRSA were all higher than those of Methicillin-sensitive Staphylococcus aureus(MSSA),the difference was statistically significant(P0.05).There were no vancomycin,tigecycline and rina amine resistant strains found,the sensitive rate was 100%.Conclusion Drug resistance situation of SAU was negative,and the characteristics of distribution should be understood timely,the monitoring of drug resistance should be strengthen,the infection and spread should be controlled effectively.
【CateGory Index】: R446.5
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