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Relatiaonship between TCM syndrome type and coagulation index of hypertension

WANG Fengmei;ZHANG Peng;SONG Bei;XU Jia;LI Qi;Department of Clinical Laboratory of Xiyuan Hospital,China Academy of Chinese Medical Sciences;  
Objective To study the correlation between Traditional Chinese Medicine(TCM)syndrome type and coagulation index of hypertension.Methods According to the diagnostic criteria related to TCM syndrome types,from September 2017 to May 2018,patients with hypertension who met the inclusion criteria were divided into the liver-fired stagnation group,the yin deficiency yang stagnation group,the yin and yang deficiency group,the phlegm-dampness group,the qi deficiency and stagnation group.We analyzed the indexes of thromboelastography(R,K,Angle,MA,LY30,EPL,CI,A30,CL30),activated partial thromboplastin time(APTT),prothrombin time(PT),prothrombin time ratio(INR),thrombin time(TT),fibrinogen(FIB),Ddimer(DD),fibrin degradation products(FDP),antithrombin(AT)and platelet(PLT)between five groups.Results The PLT of liver-fired stagnation group was higher than other groups.There were statistically significant differences between the liver-fired stagnation group,the qi deficiency and stagnation group and the yin and yang deficiency group(P0.05).The FIB,DD and FDP of the liver-fired stagnation group were lower than other groups,and there were statistically significant differences between the liver-fired stagnation group with the yin and yang deficiency group(P0.05).Conclusion Yin and yang deficiency syndrome patients of hypertensive patients were hypercoagulable compared with other groups,and liver-fired stagnation syndrome patients of hypertensive patients were hypocoagulable compared with other groups,consistent with TCM theory.
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