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Distribution and drug analysis of Gram-negative Bacteria in Shaanxi

GUI Qiaodi;ZHANG Hua;GONG Yanyan;FAN Yun;YUAN Jun;Department of Clinical Laboratory,Shaanxi Provincial People′s Hospital;  
Objective To explore the gram negative bacterial drug resistance from 2014 to 2016 in the members of Antimicrobial Resistant Investigation Net of Shaanxi province,and to guide the clinicians to use antimicrobial drugs rationally.Methods The datas of Gram-negative bacteria were collected from 2014 to2016 in the Antimicrobial Resistant Investigation Net of Shaanxi province.The datas were analyzed by software WHONET5.6.Results The Gram-negative bacterial isolates were 29 343(66.9%),32 955(68.3%)and43 206(69.9%)respectively from 2014 to 2016.The top five populations of the source were sputum,urine,blood,secretions and wound pus.From 2014 to 2016 CTX/CRO-R ECO were 64.30%,61.70%,61.40%;CTX/CRO-R KPN were 43.00%,37.80%,32.60%;CRE-ECO were 2.30%,5.70%,1.40%;CRE-KPN were6.10%,8.80%,3.20%;CRE-PAE were 32.60%,29%,27.40%;CRE-ABA were 66.20%,51.30%,58.0%.Conclusion Gram-negative bacteria are the main pathogenic bacteria of clinical separation,and the drug resistance is more common.We should strengthen the monitoring and management of bacterial resistance,and guide the clinical medication effectively.
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