Full-Text Search:
Home|About CNKI|User Service|中文
Add to Favorite Get Latest Update

Application of Triglyceride,Prothrombin Time and Uric Acid combined detection in the diagnosis of preeclampsia

SONG Qingzhen;Department of Obstetrics and Gynecology,Renqiu People′s Hospital;  
Objective To explore the clinical significance of some laboratory indicators in pre-eclampsia and provide evidence for early pre-eclampsia diagnosis.Methods 84 cases of pre-eclampsia patients were selected as observation group,and according to the similar age and gestational age,3 healthy pregnant woman was chosen as the control case for each of preeclampsia patients,from 2014.6 to 2017.10.The statistical difference of the indicators between the two groups was compared with the ttest.The Conditional Logistic regression method was used to analyze the independent influence index of preeclampsia.The ROC curve was used to analysis the value of diagnosis with Multiple laboratory indexes.Results Univariate analysis showed that pre-eclampsia patients had higher TG levels(1.86±0.77)mmol/L than control group(1.50±0.61)μmol/L(t=4.37,P=0.001).The UA level of pre-eclamptic patients(299.36±77.07)mmol/L was higher than the control group(247.02±57.04)μmol/L(t=5.72,P=0.001).The PLT level in patients was(211.65±49.70)×109/L lower than that in the control group(227.06±51.00)×109/L(t=-2.41,P=0.016).The pre-eclamptic patients had a lower PT level(11.80±3.47)s than the control group(13.64±3.85)s(t=-3.89,P=0.001).The level of other laboratory indicators in patients was not statistically different between the two groups(P0.05).Multivariate analysis showed that TG,PT,and UA were independent factors of preeclampsia.The OR(95%CI)were 1.941(1.317,2.862),0.928(0.871,0.989),and 0.994(0.991,0.998),respectively.The area under the ROC curve for the combined diagnosis was 0.872,while the areas for TG,PT,and UA alone diagnosis were 0.830,0.653,and 0.750,the combined detection effect was better.Conclusion TG,PT,UA are important indicators of the preeclampsia,Joint application of three indicators in the diagnosis of preeclampsia is of great significance.TG,PT and UA were independent predictors of preeclampsia symptoms.The ROC curve suggested that combined detection of TG,PT,and UA had better diagnostic effects on preeclampsia.
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©CNKI All Rights Reserved