Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《International Journal of Laboratory Medicine》 2019-10
Add to Favorite Get Latest Update

Research advancement on the correlation between intestinal flora and chronic kidney disease

ZHANG Yuzi;LI Minmin;Inspection Center,Clinical Medicine,the First Affiliated Hospital of Jinan University;  
With the application of hig-throughput sequencing in the field of microbiology,an increasing evidence suggests that the gut microbiota is closely related to the pathogenesis of chronic kidney disease(CKD).The pathological state of CKD can induce changes in the composition and function of the gut microbiome,that lead to generation of multiple enterogenous uremic toxins(UTs)and dysfunction of intestinal barrier.These toxins translocate into circulation stimulated systemic inflammation and increased cardiovascular risk.This review focus on the research status and related mechanisms of the microbiome in CKD pathogenesis,in the hope to provide new help for delaying the persistent progression.
【Fund】: 广东省新药筛选重点实验室开放基金项目(GDKLNDS-2018OF003)
【CateGory Index】: R692
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 2 Hits
1 Wei-Lin Wang;Shao-Yan Xu;Zhi-Gang Ren;Liang Tao;Jian-Wen Jiang;Shu-Sen Zheng;Department of Hepatobiliary and Pancreatic Surgery,First Affiliated Hospital,Zhejiang University School of Medicine;;Application of metagenomics in the human gut microbiome[J];World Journal of Gastroenterology;2015-03
2 ZHANG Jin-na1,2,LIU Ai-hua1,WU Xiao-lei2,et al.1. The Institute for Tropical Medicine, Kunming Medical University, Kunming 650031; 2. School of Chemistry Engineering, Beijing 100021, P. R. China;Combined application of metagenomics and metabonomics techniques in human gastrointestinal ecosystem[J];中国热带医学;2013-06
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 Kouichi Miura;Hirohide Ohnishi;Department of Gastroenterology,Akita University Graduate School of Medicine,Akita 010-8543,Japan;;Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease[J];World Journal of Gastroenterology;2014-23
2 William Bye;Naveed Ishaq;Terry D Bolin;Vic M Duncombe;Stephen M Riordan;Gastrointestinal and Liver Unit, Prince of Wales Hospital, Randwick 2031, New South Wales, Australia;Prince of Wales Clinical School, Randwick NSW 2031, Australia;;Overgrowth of the indigenous gut microbiome and irritable bowel syndrome[J];World Journal of Gastroenterology;2014-10
3 Marco Candela;Silvia Turroni;Elena Biagi;Franck Carbonero;Simone Rampelli;Carla Fiorentini;Patrizia Brigidi;Department of Pharmacy and Biotechnology, University of Bologna;Department of Food Science, University of Arkansas;Department of Therapeutic Research and Medicines Evaluation;;Inflammation and colorectal cancer, when microbiota-host mutualism breaks[J];World Journal of Gastroenterology;2014-04
4 Alexander Swidsinski, Vera Loening-Baucke, Herbert Lochs, Innere Klinik, Gastroenterologie, Charite Humboldt Universitat 10098 Berlin, Germany Laura P. Hale, Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA;Spatial organization of bacterial flora in normal and inflamed intestine: A fluorescence in situ hybridization study in mice[J];World Journal of Gastroenterology;2005-08
5 Qiu Deyou 1* Huang Luqi 2* 1 Institute of Forestry, Chinese Academy of Forestry, Beijing, 100091 2 Institute of Chinese Meteria Medica, China Academy of Traditional Chinese Medicine, Beijing, 100700;Metabolomics—An Important Part of Functional Genomics[J];分子植物育种;2004-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved