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《International Journal of Genetics》 2006-01
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The Advance of RNA-editing

SUN Fang,JIANG Hong,ZHENG Xiao-fei.(Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,P.R.China)Corresponding author: ZHENG Xiao-fei.E-mail: zhengxf@nic.bmi.ac.cn  
RNA-editing is a post-transcriptional process that changes the informational capacity within the RNA.To date such changes have been observed in tRNA,rRNA and mRNA molecules of eukaryotes.These processes include alterations made by nucleotide deletion,insertion and base conversion.Such changes have marked effects on gene expression,ranging from defined amino acid changes to the de novo creation of entire open reading frames.Editing can be regulated in a developmental or tissue-specific manner,and is likely to play a role in the etiology of human disease.
【Fund】: 国家自然基金资助项目(No.3020007330470899)
【CateGory Index】: R346
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Chinese Journal Full-text Database 3 Hits
1 KONG Ya-Lin,DOU Ke-Feng, ZHANG Hong-Tao, FENG Quan-Xin, ZHANG Fu-Qin,ZHAO Qing-ChuanDepartment of Hepatobiliary Surgery,Xijing Hospital,Fourth Military Medical University,Xi'an 710033,China;Expression of RNA editase of mouse lymphocytes in a co-culture system[J];Journal of the Fourth Military Medical University;2006-05
2 CAI Lei, HUO Bin-Liang, ZHANG Wei, ZHANG Fu-Qin, ZHAO Qing-ChuanDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China;Effect of siRNA-mediated silencing of ADAR1 gene on mixed mouse lymphocyte culture[J];Journal of the Fourth Military Medical University;2007-05
3 ZHAO Qing chuan 1, ZHANG De xin 1, LUO Xiao xing 1, SU Ying jun 2, YANG Jing hua 2 (1.Department of Hepatobiliary Surgery ,Xijing Hospital, Xi'an 710032, China; 2. Laboratory of Trauma Surgery, Yale School of Medicine,Yale University, New Haven;Influence of RNA editase ADAR1 on mouse lymphocyte proliferation[J];Immunological Journal;2002-04
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