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《International Journal of Genetics》 2006-01
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Advances in Researches between Genes Related to Homocysteine Metabolic and Neural Tube Defects

WANG Gang-hua,ZHENG Mei-ling.(Laboratory of Genetics,Department of Gynecology and Obstetrics,the First Affiliated Hospital,Shanxi Medical University,Taiyuan 030001,P.R.China)Corresponding author: WANG Gang-hua.E-mail: wgh791125@163.com  
Neural tube defects(NTDs) are common congenital malformations that are caused by an improper neural tube closure during embryonic early development.Neural Tube Defects are likely to result from genetic and environmental factors.Now,investigation is the focus on the relationship between factors that are related to the homocysteine metabolic and risk of neural tube defects. This paper reviews the key enzymic and important factors genes involved in the homocysteine metabolic and the relationship between the genetic polymorphism on specific sites and risk of neural tube defects.
【Fund】: 山西省科技厅攻关项目(No.041071)
【CateGory Index】: R741
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【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 Liu xuejun zhanghuiwen Chen ShengqiangGuangzhou Brain hospital;Inquiring relation between methylene tetrahydrofolate reductase (MTHFR) gene polymorphysm andthe Alzheimer desease[J];International Medicine & Health Guidance News;2003-10
2 LIANG Jian-ning1 ,CHEN Sheng-qiang2(1. People's Hospital of Xinhui City,2. Research Institute of Neuroscience , Guangzhou Medical College);Detection of the Methyltetrahydrofolate Reductase Gene in 143 Individuals[J];Academic Journal of Guangzhou Medical College;2002-01
【Co-references】
Chinese Journal Full-text Database 3 Hits
1 Zhao Fanghui Qiao Youlin (Department of Epidemiology, Cancer Hospital & Institute, CAMS & PUMC, Beijing 100021, China);Advance in etiology of cervical cancer[J];Oncology Progress;2004-01
2 HUANG Ping, ZHOU Zi yuan, MA Heng tai, LIU Jin yi, ZHOU Yan hong, CAO Jia, GE Hai yan, YU Pei wu, Toshiro Takezaki (Department of Hygiene Toxicology, College of Military Prerentive Medicine, Third Military Medical University, Chongqing 400038, China);MTHFR polymorphisms and colorectal cancer susceptibility in Chongqing people[J];Acta Academiae Medicinae Militaris Tertiae;2003-19
3 WANG Jin tao, GAO Er sheng (Institute of Planned Parenthood Research, Shanghai 200032, China.);Progress in study on relation between human papillomavirus and cervical cancer[J];Foreign Medical Sciences Section of Maternal and Child Health;2003-06
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