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《International Journal of Genetics》 2006-01
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Cell Cycle Control and Tumor

ZOU Xiang-yang~1,LI Lian-hong~2.(~1Department of Biology,Dalian Medical University,Dalian 116027;~2Department of Pathology,Dalian Medical University,Dalian 116027,P.R.China)Correspording anthor: ZOU Xiang-yang.E-mail: zouxiangyang@126.com  
Cyclins,cyclin-dependent kinases(CDKs) and cyclin-dependent kinase inhibitors(CKIs) play important roles in cotrolling cell proliferation,differentiation and apoposis.Cellular CDKs activity is tightly regulated by positive and negative factors,such as cyclins,CKIs.Defects in cell cycle regulation are common causes of the abnormal proliferation of cancer cells.These fundamental studies may result in broad applications within many different fields and may,in the long term,open a new path for cancer therapy.
【CateGory Index】: R730.2
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