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《China Medicine and Pharmacy》 2017-15
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Comparison of peritoneal dialysis and hemodialysis in the treatment of ESDN

LI Dan;GU Xuemei;DAI Huiwen;Department of Nephropathy Rheumatism,Shaoguan First People's Hospital;  
Objective To explore the effect difference of Peritoneal dialysis(PD) and hemodialysis(HD) are used to treat end-stage diabetic nephropathy(ESDN). Methods 112 patients with ESDN cured in Department of Nephrology of our hospital were selected and divided into two groups according to dialysis mode,with 43 cases in PD group and 69 cases in HD group.After 12 months of treatment,the differences among the indexes( urine volume,mean arterial pressure,serum albumin,blood creatinine,hemoglobin,serum phosphorus,serum calcium,blood potassium,blood sugar and blood lipids) and adverse events(including arrhythmias,hypertension,cardiac dysfunction,infection,bleeding, and death) of the two groups were compared. Results After 12 months of treatment,the urine volume of the PD group was significantly higher than that of the HD group(P 0.05),the mean arterial pressure and serum albumin values in the PD group were lower than those in the HD group(P 0.05),the mean arterial pressure, serum creatinine and hemoglobin values of the two groups were significantly different from those before dialysis(P 0.05),however,the urine volume and serum albumin value of patients in group PD before and after dialysis were not changed(P 0.05),and there was no significant difference in blood phosphorus,serum calcium,blood potassium,blood sugar and blood lipid between the two groups(P 0.05).The difference between the two groups was statistically significant(ESDN).The incidence of heart failure,hypertension, cardiac dysfunction and bleeding in PD group were lower than those in group HD(P 0.05),however,the incidence of infection was significantly higher than that in group HD(P 0.05),and there was no statistically significant difference in mortality between the two groups(P 0.05). Conclusion Both PD and HD can effectively treat ESDN patients,and there are advantages and disadvantages in the treatment effect.The appropriate treatment options should be selected according to the actual situation of patients.
【CateGory Index】: R587.2;R692.9
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