Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《China Medicine and Pharmacy》 2017-15
Add to Favorite Get Latest Update

Clinical analysis of allogeneic hematopoietic stem cell transplantation for treatment of adult T cell acute lymphoblastic leukemia

ZHENG Liling;OU Ruiming;Blood Specialty, Guangdong Second People's Hospital;  
Objectvie To analyze the clinical effect of allogeneic hematopoietic stem cell transplantation for treatment of adult T cell acute lymphoblastic leukemia. Methods 76 adults patients with T cell acute lymphoblastic leukemia cured in our hospital from January 2006 to December 2016 were selected and randomly divided into two groups according to random digital table method with 38 cases in each. Patients in standard group were with standard allogeneic hematopoietic stem cell transplantation, and patients in reinforcement group were treated with allogeneic hematopoietic stem cell transplantation. T cell acute lymphoblastic leukemia survival rate, survival time, platelet(blood, platelet, PLT) reconstruction time, neutrophil absolute number(ANC:absolute, neutrophil, count), reconstruction time, patient recurrence and mortality of the two groups were compared. Results The survival rate of acute lymphoblastic leukemia in T group was higher than that in standard group, P 0.05. The survival time of the intensive group was significantly longer than that of the standard group, P 0.05. The time of PLT reconstruction and the time of ANC reconstruction in the intensive group were similar to that of the standard group, P 0.05. The recurrence rate and mortality rate of the intensive group were lower than that of the standard group, P 0.05. Conclusion Allogeneic hematopoietic stem cell transplantation is effective in the treatment of adult T cell acute lymphoblastic leukemia. It can effectively improve the patient's condition, prolong the survival time, reduce the recurrence rate and mortality rate, and is worth learning.
【CateGory Index】: R733.71
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved