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《Sugarcane and Canesugar》 2017-06
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Advances in Pharmacology of Dendrobium officinale Polysaccharides

LIU Ying;CHANG Guo-wei;LIU Gui-yun;YI Xi-miao;Guangdong Provincial Bioengineering Institute (Guangzhou Sugarcane Industry Research Institute)/Guangdong Key Lab of Sugarcane Improvement & Biorefinery;  
As an excellent nourishing yin results of precious Chinese medicine,Dendrobium officinale has broad application prospects.Dendrobii officinalis polysaccharides(DOP),which is the main component of Dendrobii officinalis,draws attention of large numbers of researchers.The authors summarized the literature on DOP home and abroad in recent decade,and systemically reviewed the research advances in its pharmacological effects and mechanism.Results showed that DOP had many pharmacological effects,such as antioxidation,hypoglycemic,prevention and treatment of diabetic complications,anti-tumor,enhancing immunity,and so on.The pharmacological effects may be based on the regulation of NF-κB,PI3K/Akt,MAPK pathway.This paper intended to provide reference for further research,reasonable exploitation and utilization of Dendrobii officinalis.
【Fund】: 广西科技计划项目(桂科重1598003-3、桂科AB16380099);; 广东省酶制剂与生物催化工程技术研究中心项目;; 广东省工业技术研究院生物工程研究所科技基金面上项目(A201303)
【CateGory Index】: R285.5
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