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《Strait Pharmaceutical Journal》 2006-01
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Determination of Gardenoside in Dangzixiaoyao Capsules by HPLC

ZHOU Jin(Fuzhou Institute of Drug Control,Fuzhou,350007,China)  
OBJECTIVE The content of gardenoside in Dangzixiaoyao Capsules was determined by HPLC.METHODS The chromatographic column was Kromasil C_(18).The mobile phase was acetonitrile-water(15∶85).The flow rate was 1.0ml·min~(-1) and the detection wavelength was 238nm.The external standard and peak area method were used to determine gardenoside content.RESULTS There was a good linear relationship between gardenoside and peak area when the sample injection was from 0.30~3.00μg.The average recovery of adding sample was 98.96% and RSD was 1.32%(n=5).CONCLUSION This method is simple and believable.It can be effectively used for the quality control of Dangzixiaoyao Capsules.
【CateGory Index】: R286.0
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