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《Strait Pharmaceutical Journal》 2006-01
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Determination of Bumetanide Tablets by HPLC

RUAN Bao-qiang(Fuzhou Institute for Drug Control 350007,China)  
OBJECTIVE To develop a method for determining the contents of bumetanide tablets by HPLC.METHODS The chromatographic column was Hypersil ODS2.The mobile phase was methanol-water(75∶25).The flow rate was 1.0ml·min~(-1) and the detection wavelength was 328nm.RESULTS There was a good linear relationship between bumetanide and peak area when the sample injection was from 0.208μg~1.040μg.The average recovery of adding sample was 100.04% and RSD was 1.41%(n=9).CONCLUSION This method is simple and believable.It can be effectively used for the quality control of Bumetanide Tablets
【CateGory Index】: R927.2
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 CHEN Jian-Qin,CHEN Qiu-Hon(Nanning Muxicipal Institute for Drug Control,Guangxi Nanning 530001 China);Ftibamzone liniment determination of by HPLC[J];Chinese Journal of Hospital Pharmacy;2003-10
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 LI Wei-Chen,SUN Yu-hua(Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai 200062,China);Determination of bumetanide for injection by rapid tandem mass spectrometry[J];Strait Pharmaceutical Journal;2009-06
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