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《Strait Pharmaceutical Journal》 2006-01
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Study on Adsorption of Chlorogenic Acid with Macroporous Resin

WANG-Fang,LIU Xiao-hua,ZHAO Hao-ru(Institute of Traditional Chinese Medicine,China Pharmaceutical University,Nanjing 210038,China)  
OBJECTIVE To select the type of macroporous resin and the process parameters for purifyication of chlorogenic acid in Flos Lonicerae.METHODS The content of chlorogenic acid was determined by HPLC.Properties of adsorption and desorption,adsorption dynamicsand factors affecting the adsorption were investigated by static adsorption method.RESULTS The macroporous resin of HPD100 had the best performance;although deportion efficiency of HPD 450 was the highest,both of its adsorptive quantity and efficiency were lower.The adsorption quantity was more in acidic solution than that in alkalic solution.CONCLUSION HPD 100 was a choice of the optimal macroporous resin;the appropriate adsorption is performed in pH3 acidic solution.
【CateGory Index】: TQ461
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