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《Journal of Hebei Normal University(Natural Science Edition)》 2008-03
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Syntheses of Spherical Molecularly Imprinted Polymers and Their Molecular Recognition for Sulfadiazine

JIANG Ji-gang,WANG Lei,WEI Guang-cheng (Department of Chemistry,Binzhou Medical College,Shandong Binzhou 256600,China)  
Taking sulfadiazine as template molecular,spherical molecularly imprinted polymer(MIP) were prepared according to molecularly imprinted technology.By Scatchard mode,the dissociation constant of MIP at binding site is 8.6 μmol/L,and the max binding capacity of MIP is 185.7 μmol/g.Binding isotherm equation tallies with Longmuir equation,and the selective binding ability of MIP decreases with the increase of the polarity in solution,which indicate that non covalent bond plays a great role in molecular recognition.
【Fund】: 山东省卫生厅科技基金(2003CAICFB4);; 滨州医学院科技基金(BY2006KJ12)
【CateGory Index】: O631.3
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8 ZHANG Shengzu,FU Xinjian,WANG Hong,YANG Yajiang(School of Chemistry and Cghemical Engineering,Huazhong University of Science and Technology,Wuhan 430074);CHOLESTEROL IMPRINTED POLYMERIZED ORGANOGEL FORMED BY POLYMERIZABLE GELATOR AND ADSORPTION ABILITY[J];Acta Polymerica Sinica;2009-03
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