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《Heilongjiang Animal Science and Veterinary Medicine》 2010-01
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Effect of estradiol on IgA~+ cells in small intestine mucosa of rat

YAN Jin-kun1,2,YANG Wen-xing3,LI Jing-hua4,CHEN Yao-xing1(1.College of Veterinary Medicine,China Agricultural University,Beijing 100094,China;2.College of Agriculture,Hebei University of Engineering,Handan 056038,China;3.Animal Husbandry and Fishery Bureau of Guantao County,Guantao 057750,China;4.Animal Husbandry and Fishery Bureau of Renqiu City,Renqiu 062550,China)  
To explore the effect of estradiol on IgA+ cells in small intestine mucosa of the rat,immunohistochemistry was used in the experiment,and the amount of IgA+ cells of female Wistar rats that had been given different dosage of estradiol was calculated.The result showed that compared with control group,the IgA+ cell number of the rats whose ovary had been removed has increased remarkably while compared with OVX group,the IgA+ cell number of the rats that had been given proper dosage of estradiol has increased remarkably.A conclusion,therefore,has been reached that removing ovary can reduce the immunity of small intestine mucosa in rats while giving dosage of estradiol can change the effect for better.
【Fund】: 国家自然科学基金项目(3047124730671514)
【CateGory Index】: S852.23
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1 YAN Jin-kun1,2,CHEN Yao-xing1,WANG Zi-xu1(1.College of Veterinary Medicine,China Agricultural University,Beijing 100193,China;2.College of Agriculture,Hebei University of Engineering,Handan 056038,China);Effect of Estrogen on Structure of Mucosal Epithelium and Number of Intraepithelial Lymphocytes and Goblet Cells in Small Intestine of Rat[J];Chinese Journal of Animal and Veterinary Sciences;2008-09
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