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《Heilongjiang Animal Science and Veterinary Medicine》 2018-01
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Progress in the research of mitochondrial dysfunction caused by stress

LI Yang;GUO Yao;LIU Zhongying;LI Xiangyun;WU Zhonghong;College of Animal Science and Technology,Hebei Agricultural University;College of Animal Science and Technology,China Agricultural University;  
With changes of social environment and acceleration of life pace,as well as changes of livestock breeding environment and pattern,human and livestock are frequent suffering different degrees of stress from the various sources. It can cause physiological and pathological changes in organism. Mitochondrion is one of the most sensitive organelles to various organism damages,and mitochondrial dysfunction is easy to happen when the organism or cell suffers from stress. The present review summarized recent progress of effects on cell mitosis and proliferation,metabolism and programmed-cell-death( apoptosis) caused by stress through impairing mitochondrial morphological structure and distribution,changing the balance of mitochondria fission and fusion,affecting ATP synthesis and the intrinsic mitochondrial apoptosis pathway.
【Fund】: 国家重点研发计划项目(2016YFD0500506);; 国家兔产业技术体系项目(CARS-44-D-4)
【CateGory Index】: S852.3
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