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《Heilongjiang Medical Journal》 2002-01
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Expression and Its Clinical Significance of P_(53) in Pregnancy Trophoblast Tumor

NI Ya-li, LIU Zhen (The Hospital of Women and Children Health Care of Gansu Province, Lanzhou 730050, China)  
Objective To try to find the predict data of hydatidiform mole to indicate the clinical treatment after detection P 53 expression and correlation of the hydatidiform mole(HM), invasive hydatidiform mole(iHM), choriocarcinoma and normal chorion. Methods The P 53 expression was detected with histoimmunochemical SP method in 20 cases of normal choroin, 40 cases of HM, 20 cases of iHM and 20 cases choriocarcinoma. The statistics was performed with rank test of order materials. Results The P 53 positive cell counts of choriocarcinoma, iHM and HM were higher than that in normal chorion (P0.01). The P53 positive cell counts of choriocarcinoma and iHM were higher than that of HM (P0.01). That of HM was higher than normal chorion (P0.05).Conclusion The positive rate of expression of P 53 in chorion disease was positive correlated with the proliferating and malignant degree of the disease. P 53 might be an important and available method to predict the canceration, its degree and prognosis. P 53 gene expression could be according as to assess the effect of chemotherapy and prognosis as P 53 could be in fact on mutation.
【CateGory Index】: R730.2
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Chinese Journal Full-text Database 1 Hits
1 Chi Jinghua,Ji Xiangrui.Department of Pathology,Medical College of Qingdao University,Qingdao 266021;Relationship between the p53,p21~(CIP1),p185 protein expression and malignant transformation in hydatidiform mole[J];Current Advances In Obstetrics and Gynecology;2003-04
Chinese Journal Full-text Database 10 Hits
1 WANG Cheng_run 1 ,MIN Li 2 ,WU Wei 3 ,et al (1.Department of Chemistry and Biology,Huainan Normal College,Huainan232001,China;2.Library,Huainan Normal College,Huainan2320001,China;3.Biological Engineering Center,Xuzhou Normal University,Xuzhou221116,China);Effects of Holmium Element on DNA Lesion of Mice Liver Cells in Vivo[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-04
2 ZHU Guo-qi,TANG LI-jian,WANG Lei,SU Jing-jing,WANG Ning,PENG Dai-yin,LI Qing-lin(Anhui College of Traditional Chinese Medicine & Anhui Key Laboratory of Modern Chinese Materia Medica,Anhui Hefei 230038,China);Study on Baicalin Induced Apoptosis of Human Breast Cancer Cell Line MDA-MB-231[J];Journal of Anhui Traditional Chinese Medical College;2008-02
3 GAO Yao-jie HU Yu-quan SI Xiu-rui WANG Li -na LI Jing-zhi(Department of Gynaecology, Hospital A ffiliated to Henan College of Traditiona al Chinese Medicine);THE ANALYSIS OF THE CLINICAL TREATMENT OF 246 CASES OF NALIHGN ANT TROPHOBLASTIC TUMOR BY THE COMBINATION OF WESTERN AND TRADITIONAL CHINESE MENICINE[J];Chinese Journal of Cancer;1988-05
4 NIU Yan-ling,CAO Sheng-li,JIANG Yu-yang ,DU Wei ,ZHAO Yu-fen Key Laboratory of Bioorganic Phosph orus Chemistry,Ministry of Educati on,Department of Chemistry,School of Life Sciences and Engineering,Tsinghua University,Beijing 100084,P.R.China;Apoptosis of K562Cell Induced by N-p hosphoryl Dipeptide Methyl Ester[J];Chinese Journal of Cancer;2002-08
5 Xu Yang1, He Bin2, Wang Ya- Jie1, Fu Qiang1 1. Department of Oncology, Changhai Hospital,The second Military Medical University, Shanghai,200433, P.R.China 2. Department of Cardiothoracic Surgery,Changhai Hospital,The Second Military Medical University, Shanghai,200433, P.R.China;Effect of Herceptin Combined with Doxorubicin on Rat Cardiotoxicity[J];Chinese Journal of Cancer;2004-04
6 Zhang Shifu, Xie Qun, Yao Min,Wang Ping, Xiong Shigang, Liu Sengui (Department of Pathology, Bengbu Medical College, Anhui );HISTOPATHOLOGIC AND β-HCG QUANTITATIVE ANALYSIS OF INVASIVE MOLE[J];Journal of Bengbu Medical College;1990-01
7 Zhang Suifu, Xie Qun, Yao Min, Wang Ping, Xiong Shigang, Liu Sengui (Department of Pathology, Bongbu Medical College, Anhui );A QUANTITATIVE STUDY OF β-HCG IN TROPHOBLASTIC TUMORS[J];Journal of Bengbu Medical College;1990-01
8 Xie Qun, Zhang Shifu, Yao Min, Wang Ping, Xiong Shigang, Liu Sengui (Department of Pathology, Bengbu Medical College, Anhui );STUDIES ON THE β-HCG AND CLINICAL PATHOLOGY OF HYDATIDIFORM MOLE[J];Journal of Bengbu Medical College;1990-01
9 Xiong Shigang, Yao Min, Wang Ping (Department of Pathology, Bengbu Medical College, Anhui );CHORIOCARCINOMA: CELL β-HCG LEVEL AND KINETOMORPHOLOGY[J];Journal of Bengbu Medical College;1990-01
10 WANG Xin-ming~1, JIANG Ying~1,TAN Yan~ 2,XU Li~3,FANG Yan-qiu~2 (1. Department of Oncology, Second Hospital,Jilin University, Changchun 130041,China; 2. Department of Central Laboratory, Frist Hospital,Jilin University, Changchun 130021,China; 3. Department of Laboratory, Second Hospital,Jilin University, Changchun 130041,China);Relationships between soluble Fas levels and breast diseases[J];Journal of Jilin University of (Medicine Edition);2005-02
China Proceedings of conference Full-text Database 1 Hits
1 Wen Zhu~1,Hu Guo-zhu~2,He Dan~2,Yu Huo~1,Rong Ji-ping~1 (1.Jiangxi Institute of Medical Science,Nanchang University,Nanchang 330006,P.R.China;2. Institute of Clinical Medicine of The Jiangxi Province People's Hospital,Nanchang,330006, P.R.China);EFFECT OF LIGUSTRAZINE HYDROCHLORIDE ON PREVENTING FROM THE SUPPRESSION AND APOPTOSIS OF BONE MARROW STROMAL CELLS INDUCED BY VINCRISTINE[A];[C];2009
Chinese Journal Full-text Database 10 Hits
1 Zhang Xiaowei,Zhang Lizhu, Zhou Xianmei,et al (Department of Obstetrics and Gynecology of the Third Hospital,Peking University,Beijing 100083);The relationship between the Y chromosome positive and the risk of developing persistent gestational trophoblastic disease of hydatidiform mole[J];Beijing Medical Journal;2002-02
3 LIU Min reviewer, LIU Wei reviser (Department of Endocrinology and Metabolism, Renji Hospital, Shanghai Second Medical University, Shanghai200127, China);Current Research Progresses of FOXC2[J];Acta Universitatis Medicinalis Secondae Shanghai;2005-07
4 FU Yan 1,3)** , DENG Wei Guo 2) , LI Yi Yang 1) , LI Yu Lin 3) , N.MIURA 4) ( 1) Department of Obstetrics and Gynecology, First Hospital, Jilin University, Changchun 130021, China; 2) Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun 130021,China; 3) Department of Pathology, School of Preclinical Medicine, Jilin University, Changchun 130021,China; 4) Department of Biochemistry, Hamamatsu University School of Medicine, Hamamatsu 431 3192, Japan);Effect of Fox c2 on Aortic Arch Development[J];Progress In Biochemistry and Biophysics;2003-05
5 XU Jian-yun,SHI Yi-fu (Affiliated Hospital of Gynecology and Obstetrics,College of Medical Sciences,Zhejiang University,Hangzhou,310006,China);Exprssion of nm23H_1 and PCNA in gestational trophoblastic tumors and its clinical significance[J];JOURNAL OF PRACTICAL ONCOLOGY;2000-02
6 Yang Xingsheng,Zhang Zhenguo,Zhang Youzhong,et al.The Affliated Hospital of Shandong Medical University,250012;The predicting evaluation of c Ha ras,c erbB 2,p53 and nm23 gene products in the malignant transformation of hydatidiform mole.[J];CURRENT ADVANCES IN OBSTETRICS AND GYNECOLOGY;1998-02
7 WU Wei-ping~1,ZHENG Zhao-xun~2(1.Department of Pathology,Nanjing Maternal and Neonatal Health Hospital,Nanjing 210004,China; 2.Department of Pathology,Jiangsu Province People's Hospital,Nanjing 210000,China);Relationship of matrix metalloproteinases and their tissue inhibitor with invasiveness growth of trophocytes[J];Chinese Journal of Diagnostic Pathology;2006-03
8 ZHANG Xiu-Fen,CHEN Su-Qin,ZHANG Jie-Ying,et al.Department of Obstetrics and Gynecology,Hebei Medical University,Shijiazhuang 050000,Hebei,China;The expression of e-cadherin gene relate with malignant transformation in hydatidiform mole[J];Maternal and Child Health Care of China;2008-13
9 LI Zhiying *, XIANG Yang, DAI Li, et al. * Department of Obstetrics and Gynecology, Hubei Sanxia Medical College, Hubei Province 443007, China;Prediction of Malignant Transformation of Hydatidiform Mole by mRNA Determination of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases[J];Chinese Journal of Obstetrics And Gynecology;2000-09
10 TANG Li xia *, WANG Min,MA Jian wei. * Department of Gyncology and Obstetrics, Dalian Sixth Hospital, Dalian 116001, China;Relation between COX-2 protein expression and biologic behavior of ovarian carcinoma[J];Chinese Journal of Oncology;2003-03
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 CHI Jing-hua, JI Xiang-rui (Department of Pathology, Qingdao University Medical College, Qingdao 266021, China);;EXPRESSION OF P21~(CIP1) AND P53 PROTEINS IN MALIGNANT TRANSFORMATION OF HYDATIDIFORM MOLE[J];Acta Acadimae Qingdao Umvesitatis;2004-01
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