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《JOURNA OF HENAN MEDICAL UNIVERSITY》 1994-01
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Study on the mouse forestomach neoplasms induced by coal tar pitch smoke

Wang Jiang;Zhao Qingxia;Wei Li;Li Xinrong;Zhang Hongxin(Department of Pathology,Henan Medical University;Zhagzhou 450052)  
Kuming mice were divided at random into two groups.The mice in group A inhaled coal tar pitch smoke(CTPS)in a sealed box 3 hours a day for 4 months.The average concentration of CTPS in the box was 0.17mg/L.Group B was taken as control.The whole experiment lasted for 8 months.6mice in each group were killed respectively on the third and the sixth month,and the rest were killed at the end of the experiment.The incidence of mice forestomach neoplasm in group A was 72.50%(29/40).There were 7 squamous cell carcinomas(17.5%)among them and the rest,papiollomas.The study suggests that CTPS might have strong tumorigenic effect on the forestomach of mouse and might be a potential carcinogenic factor to the esophagus.
【Fund】: 河南省教委自然基金
【CateGory Index】: R735.202
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Wang Jiang et al (Department of Pathology Henan Medical University Zhengzhou 450052);THE EFFECTS OF SO_2 ON THE CARCINOGENESIS OF MOUSE LUNG CANCER INDUCED BY PITCH SMOKE[J];Henan Medical Research;1993-03
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 Wang Jiang Zhao Qing-xia Wei Li Li Xin-rong Zhang Hong-xin(Department of Pathology,Henan Medical University,Zhengzhou 450052);STUDY ON THE INDUCTION OF FORESTOMACH NEOPLASM IN MICE BY INHALATION OF COAL TAR PITCH SMOKE[J];HENAN MEDICAL RESEARCH;1994-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 BA Yue 1, WU Yi-Ming 1, ZHOU Xiao-Shan 2 (1. Department of Occupational Health, Public Health College, Zhengzhou University, Zhengzhou 450052,China; 2. Department of Biochemistry, Peking Union Medical College);Expression of melanoma antigen-a mRNA in coal tar pitch-induced lung cancer tissues in mice[J];Academic Journal of Second Military Medical University;2002-09
2 WU Bo MA Jie SHUN Gui qin ZHOU Xiao jun (The Department of Pathology,Nanjing Jinling Hospital,Nanjing 210002,China.);The ultrastructural observation of the apoptosis on liver cells[J];Journal of Chinese Electron Microscopy Society;2000-06
3 Yang Jianming; Jiang Xuezhi; Jin Taiyi et al (Department of Occupational Health, Shanghai Medical University, Shanghai 200032);Renal Toxicity of Lead and Its Relationship with Cells Apoptosis[J];TRACE ELEMENTS SCIENCE;1998-04
4 ZHANG Tai_jiang,MAYong_zhi,XIAO Wen,et al,Anyang Institute of Occupational Dis_ eases Prevention,Anyang455000;Investigating the biomembrane injury in workers exposed to polycyclic aromatic hydrocarbons(PAHs)[J];Guangxi Journal of Preventive Medicine;2003-04
5 Cheng Yuankai (Institute of Industrial Health, Anshan Iron and Steel Co.);EXPERIMENTAL STUDY ON THE INDUCTION OF RAT LUNG CANCER BY COAL TAR PITCH PARTICULATES[J];Industrial Health and Occupational Diseases;1985-02
6 Hai Tao et al(Inst. of Occup. Med., Tongji Med. Univ., Wuhan 430030 China);STUDY ON THE DAMAGE OF CELL GENOTOXICITY INDUCED BY COKE OVEN EMISSION IN WORKERS[J];INDUSTRIAL HEALTH AND OCCUPATIONAL DISEASES;1998-06
7 Wang Xinchao et al\= (Division of Labor Health,Henan Medical University,Zhengzhou 450052 China) \=;Detection of Serum ras P21 Level inCTP(Coal Tar Pitch) Exposed Workers[J];INDUSTRIAL HEALTH AND OCCUPATIONAL DISEASES;1999-03
8 ZHOU Fang 1) ,WU Yiming 1) , LI Jianduan 2) ,CHEN Chen 1) ,WANG Xinchao 1) 1)Department of Occupational Health and Health Toxicology,Henan Medical University,Zhengzhou 450052 2)Department of Biochemistry,Henah Medical University,Zh;Expression of telomerase activity in rat lung cancer induced by coal tar pitch[J];JOURNA OF HENAN MEDICAL UNIVERSITY;2000-03
9 WU Yiming, LI Shi'en, MENG Aimin, YAO Wu, CHEN Chen, YANG Tingzhang Department of Occupational Health and Health Toxicology,Henan Medical University, Zhengzhou 450052;Determination of damage index of biomembrane and T-lymphoblast subgroup in patients exposed to polycyclic aromatic hydrocarbons[J];JOURNA OF HENAN MEDICAL UNIVERSITY;2000-03
10 Xu Haowen,Guo Yunliang ( Institute of Cerebrovascular Disease,Medical College, Qingdao University,Qingdao 266003 );DIFFERENCE BETWEEN NEURON AND ENDOTHELIAL CELL APOPTOSIS AND THE EXPRESSION OF BCL 2 AND P53 AFTER CEREBRAL ISCHEMIA REPERFUSION IN RATS[J];Chinese Journal of Anatomy;2001-05
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 WU Yanming,ZHANG Dexing,HE Xinghong,LU Zhigen Department of Basic Sciences,Guangdong Pharmaceutical College,Guangzhou 510006,China;Effects of manganese exposure on liver in rats[J];Journal of Hygiene Research;2009-01
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