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Comparative study of immunological function of thymus extract from patients with myasthenia gravis and normal individuals

Zhang Guorong;Zhang Qingyong;Yang Junjie;Li Shixiao;Zhang Jing(Department of Anatomy,Henan Medical University,Zhengzhou 450052 Department of Chest Surgery,the Second Affiliated Hospital,Henan Medical University,Zhengzhou 450003 Department of Microbiology  
The effects of thymus extract obtained from the patients with myasthenia gravis(TEMG)and the normal individuals and diluted to various concentrations ,on the proliferation of normal human peripheral blood Iymphocytes were evaluated with  ̄3H-TdR incorporation assay.The results showed that the immunological function of thymus in childhood decreased to certain degree and almost fully lost in aduIt.Hyperplastic TEMG had significant suppressive and enchancement effect on PHA-induced normal human PBL proliferation.This paper explains and supports the effects of thymectomy on the treatment of hyperplastic myasthenia gravis,
【CateGory Index】: R746.103
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