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《Journal of Chinese Practical Diagnosis and Therapy》 2013-05
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Features and prognostic significance of electrocardiography in acute myocardial infarction patients younger than 35 years

HUANG Ji*,QIAN Hai-yan,LI Zhi-zhong,ZHANG Jing-mei(*Department of Cardiology,Beijing Anzhen Hospital Affiliated to Capital Medical University,Beijing 100029,China)  
Objective To evaluate the features of electrocardiography(ECG) of acute myocardial infarction(AMI) patients younger than 35 years and its relationship with prognosis.Methods A total of 117 AMI patients younger than 35 years were followed up the major adverse cardiovascular events(MACE) in one year after being discharged,and were divided into MACE group and non-MACE group.The clinical data,coronary angiography results and ECG features at admission were compared and analyzed.Results There were significant differences in body mass index,smoking history,family history of coronary heart disease,diabetes mellitus proportion,serum creatinine,hemoglobin,left ventricular ejection fraction,multiple branches and left main lesions between MACE group and non-MACE group(P0.05).Multivariate logistic regression analysis showed corrected QT interval(HR=1.5,P=0.03) and lateral ST-depression(HR=4.66,P=0.00) were obviously correlated with 1-year MACE.After adjustment for all risk variables,corrected QT interval(HR=1.2,P=0.04) and lateral ST-depression(HR=3.6,P=0.01) were correlated with 1-year MACE.Conclusion Corrected QT interval and lateral ST-depression are independent predictors of 1-year MACE in AMI patients younger than 35 years.
【Fund】: 国家自然科学基金(81000130);国家自然科学基金(81000091);; 北京市卫生局青年科学研究资助项目(QN2010-010);; 北京新星计划(2008-B78 北京市科学技术委员会)
【CateGory Index】: R542.22
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