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《Hunan Journal of Traditional Chinese Medicine》 2015-01
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Analysis of TCM syndrome types of insomnia in elderly patients with type 2 diabetes

WEN Wei-bo;FANG Fang;SUN Zhao-hui;Yunnan Provincial Hospital of Traditional Chinese Medicine;  
Objective: To investigate the distribution characteristics of traditional Chinese medicine( TCM) syndromes of insomnia in elderly patients with type 2 diabetes. Methods: According to the established inclusion criteria and exclusion criteria,300 patients aged over 60 years who had type 2 diabetes and insomnia. Their general status and history of type 2 diabetes were investigated,and the clinical symptoms,tongue veins,body mass index,waist circumference,fasting blood glucose,glycosylated serum protein,and glycosylated hemoglobin were recorded. Frequency analysis and k- means clustering,as well as syndrome element differentiation,were used to investigate the distribution characteristics of TCM syndromes of insomnia in elderly patients with type 2 diabetes,and factor analysis was used to investigate the common factor characteristics of different groups of TCM syndromes. Results:( 1) Characteristics of clinical symptoms and tongue veins: the symptoms with a frequency of 60% included insomnia,dry mouth,thirst and frequent drinking,dizziness,constipation,nocturia,fatigue and weakness,and limb numbness; the features of tongue veins with a frequency of 60% were fine veins and white fur.( 2) Results of k- means clustering: the significance of clustering for syndrome differentiation was the best when the number of clusters was7; TCM syndromes could be clustered into qi deficiency,yin deficiency,fire heat,deficiency of both qi and yin,kidney yin- yang deficiency,liver yin deficiency,and deficiency of kidney- essence.( 3) Results of factor analysis: the general condition of blood glucose control is the common factor that all groups of TCM syndromes shared; other common factors varied between different TCM syndromes,substantially between some ones. Conclusion:( 1) The TCM syndromes of insomnia in elderly patients with type 2 diabetes can be clustered into qi deficiency,yin deficiency,fire heat,deficiency of both qi and yin,kidney yin- yang deficiency,liver yin deficiency,and deficiency of kidney-essence.( 2) These groups of TCM syndromes have different common factors,which vary substantially between some TCM syndromes.
【CateGory Index】: R259
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