Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Hunan Journal of Traditional Chinese Medicine》 2015-01
Add to Favorite Get Latest Update

SOFA- based evaluation of prognostic impact of detoxicating and stasis- resolving granules in patients with severe chronic hepatitis

LONG Fu-li;MAO De-wen;CHEN Xiao-ming;ZHANG Rong-zhen;YANG De-fen;YI Min-ming;XU Gang;The First Affiliated Hospital of Guangxi University of Chinese Medicine;  
Objective: To observe the prognostic impact of detoxicating and stasis- resolving( DTSR) granules in severe chronic hepatitis patients with different Sequential Organ Failure Assessment( SOFA) scores. Methods: A total of92 patients with severe chronic hepatitis who met the diagnostic criteria were selected and were randomly divided into treatment group( n = 46) and control group( n = 46) according to the SOFA scores before treatment. The treatment group received DTSR granules and basic Western medicine treatment,while the control group received basic Western medicine treatment alone. The SOFA scores before and after treatment were recorded and subjected to comparative analysis. Results: The treatment group had a significantly lower maximum SOFA score than the control group( P 0. 05). After treatment,the surviving patients had a significantly lower SOFA score than the dead patients[( 6. 23 ±2. 87) vs( 9. 53 ± 2. 86),P 0. 001) ]. Conclusion: The mortality of patients with severe chronic hepatitis rises with increasing SOFA score. DTSR granules can significantly decrease the SOFA score in patients with severe chronic hepatitis,further proving that the prescription can improve the prognosis and reduce the mortality of patients.
【Fund】: 广西壮族自治区卫生厅自筹课题(编号:Z2012155);; 广西中医药大学普通课题(编号:P2012045)
【CateGory Index】: R285.6
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 Mao Dewen Qiu Hua The First Affiliated Hospital,Guangxi TCMUniversity,Nanning530022 Li Ya The First Affiliated Hospital,Hunan TCMUniversity,Changsha410007 Liao Shuqi The Changsha Zymotic Hospital Changsha410011;Observation of Curative Effect on Severe Hepatitis with Jie Du Hua Yu Granule[J];Guangxi Journal of Traditional Chinese Medicine;2004-04
Chinese Journal Full-text Database 10 Hits
1 Lu'an People's Hospital,Lu'an 237005,Anhui GAO Qian-feng;Clinical study on the treatment of combination of Tuihuang Tang and Diammonium Glycyrrhizinate on intrahepatic cholestasis[J];Journal of Anhui Health Vocational & Technical College;2006-05
2 Department of Infectious disease, Lu'an People's Hospital, Lu'an 237005, Anhui ZHAO De-cheng, LI Guang-hai, DU Jun;Treatment Experience of the Patients with Refractory Ascites in 57 Cases Treated by Ultrafiltration of Ascites and Peritoneal Reinfusion[J];Journal of Anhui Health Vocational & Technical College;2009-03
3 Anhui Suzhou Municipal Hospital, Suzhou 234000, Anhui LIU Xiangyun;The Impact of Nursing Intervention On Depressed Patients Of Chronic Hepatitis B[J];Journal of Anhui Health Vocational & Technical College;2009-03
4 People's Hospital of Bozhou City,Bozhou 236800,Anhui ZHAO Tai-yun,TU Jing;The clinical observation on Combined treating upper gastrointe hemorrhage in liver cirrhosis[J];Journal of Anhui Health Vocational & Technical College;2011-03
5 YAN Peng-you The People's Hospital Wangjiang County of Anhui Province,Wangjiang 238300,Anhui;Clinical research of hospital-families-patient's model to improve the prognosis of patients with liver cirrhosis[J];Journal of Anhui Health Vocational & Technical College;2011-05
6 Lu Zhaohui, Zhang Quxia, Chang Lifei, et al Department Of Infectious Diseases, Anhui Provincial Hospital, Hefei 230001;A clinical assessment of artificial liver supporting systems on patients with fatal hepatitis[J];Anhui Medical Journal;2003-01
7 Kong Jianxin, Wang Baolong Department of Laboratory,Anhui Provincial Hospital, Hefei 230001;Study on the relationship between chronic hepatitis B and HLA-DRB1 allele[J];Anhui Medical Journal;2004-05
8 Peng Jun , Li Xiaoyue , Zhang Erchun, et al Department of Pathology,Anqing Affiliated Hospital of Anhui Medical University,Anqing 246003;The relations between pathology diagnoses of chronic hepatitis B and serums hyaluronic(HA),laminin(LN) and collagen Ⅳ (CIV)[J];Anhui Medical Journal;2008-06
9 Zhao Zonghao, Mei Qiao, Wu Jun, et alAnhui Provincial Hospital, Hefei 230001;A initial research on the mechanism of melatonin against rat liver fibrosis[J];Anhui Medical Journal;2009-03
10 Tang Hong,Tang Deping Hefei the Sixth People's Hospital,Hefei 230022,China;The clinical value of color Doppler ultrasound in the diagnosis of liver fibrosis in chronic hepatitis B[J];Anhui Medical Journal;2010-02
China Proceedings of conference Full-text Database 10 Hits
1 Hospital of Jiangxi Medical College of Gastroenterology Xiongming Fang,Han Yubin~1,Hu Jia~1, Wang Liping,Xie Hui group~ 2,Xu Yun~ 2,Amateur Training~2,key wind Mei,Yang Satellite.;Softening Hard removing blood stasis of schistosomiasis cirrhosis Affiliated[A];[C];2010
2 YIN Yan-yao,ZONG Ya-li,LIN Yun-hua Ninth Hospital of Nan Chang,Nanchang 330002,China;Clinical research of Chinese herbal retention enema by Total Colonic Dialysis in Treating Hepatic encephalopathy[A];[C];2010
3 Xiao yingqun;To study diagnosing significance of pathology in occult hepatitis B[A];[C];2010
4 LOU Jian-guo,FU Zhi-min,GON Qi-ming,et al.The Tradition Medical Hospital of Jinhua City;Clinical study of sequential treatment with Wenyang Huayu Decoction and lamivudine on patients with chronic hepatitis B[A];[C];2011
5 A yongjun Li Li Li Xiaoyan,Department of Hepato-Bilio Surgery,the Second Hospital Affiliated to Kunming Medical College,Kunming 650101,China;Application of Artificial Liver Support System in Liver Failure of Severe Hepatitis and Liver Transplantation[A];[C];2004
6 YU JianWu Ll XiaoGuang ZHAO YongHua, Department of Infectious Diseases,The Second Affiliated Hospital,Harbin Medical University,Harbin 150086,China;Clinical study of patients with severe hepatitis treated with protein adsorbent recirculating system[A];[C];2005
7 WANG Shuqin YU JianWu lvlingying. Department of Infectious Diseases,The Second Affiliated Hospital,Harbin MedicalUniversity,Harbin 150086,China;Causes and nursing care for the change of blood pressure undergoing plasma exchange[A];[C];2005
8 YU JianWu WANG GuiQiang ZHAO YongHua, Department of Infectious Diseases,The Second Affiliated Hospital,Harbin Medical University,Harbin 150086,China;Prognosis of Patients with fulminant Hepatitis after plasma exchange treatment using MELD scoring system[A];[C];2005
9 LU Zhao-hui ZHANG Qu-xia CHANG Li-Fei, Department Of Infectious Diseases,Anhui Provincial Hospital,Hefei 230001;A clinical assess of artificial liver supporting systems on patients with fatal hepatitis[A];[C];2005
10 YUAN Chun HUANG chang-xing LIAN Jian-qi. The Center of Diagnosis and Treatment for Infectious Diseases of PLA,Tangdu Hospital,Fourth Military Medical University,Xi'an 710038,China;Study on detection of bacterial DNA in ascites of patients with cirrhosis by PCR[A];[C];2005
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved