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《Hunan Journal of Traditional Chinese Medicine》 2015-01
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Effects of Sanhuang lotion on serum levels of IL- 17,IL- 23,and TGF-β in patients with eczema

YANG Ji-ping;WANG Rui-ke;The First People's Hospital of Jining;  
Objective: To observe the efficacy of Sanhuang lotion in t he treatment of eczema and its effects on serum levels of interleukin- 17( IL- 17),interleukin- 23( IL- 23),and transforming growth factor- β( TGF- β)among patients with eczema. Methods: Sixty patients with eczema were randomly divided into treatment group( n =30) and control group( n = 30). The treatment group received fumigation- washing therapy with Sanhuang lotion,while the control group was orally given cetirizine hydrochloride tablets. The course of treatment was 30 d for both groups. The efficacy was statistically analyzed after treatment. Results: The treatment group had a significantly higher overall response rate than the control group( 93. 3% vs 70. 0%,P 0. 01). Both groups showed significant decreases in Eczema Area and Severity Index and pruritus score after treatment( P 0. 05),and the treatment group had a significantly higher decrease than the control group( P 0. 05). Both groups showed significant decreases in serum levels of IL- 17,IL- 23,and TGF- β after treatment( P 0. 05),and the treatment group had a significantly higher decrease than the control group( P 0. 05). Conclusion: Sanhuang lotion has satisfactory efficacy in the treatment of eczema.
【Fund】: 山东省济宁市科技局计划资助项目(编号:ZY2012001)
【CateGory Index】: R285.6
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