Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Hunan Journal of Traditional Chinese Medicine》 2015-12
Add to Favorite Get Latest Update

Clinical efficacy of Anchang Decoction in treatment of liver depression and spleen deficiency syndrome of diarrhea-predominant irritable bowel syndrome

HUANG Shi;LIANG Jian;DENG Tian-hao;ZHANG Tao;LI Yi-zhong;ZHU Zhao-yang;ZHENG Dong-lin;SONG Jie;MENG Xiao-bing;LIU Peng;LIN Chun-li;Hunan University of Chinese Medicine;Huadong Branch of Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine;The Affiliated Hospital of Hunan Academy of Chinese Medicine;Konggang Branch of Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine;  
Objective: To investigate the clinical efficacy of Anchang Decoction in the treatment of the liver depression and spleen deficiency syndrome of diarrhea- predominant irritable bowel syndrome( IBS- D) based on the evaluation of therapeutic effect on traditional Chinese medicine( TCM) syndrome,as well as the role of liver- soothing treatment in the liver depression and spleen deficiency syndrome of IBS- D,and to provide a basis of evidence-based medicine for TCM treatment of IBS- D. Methods: A total of 120 IBS- D patients with the syndrome of liver depression and spleen deficiency were randomized into four groups: group A( Anchang Decoction group),group B( Tongxieyaofang group),group C( Chaihu Shugan Powder group),and group D( pinaverium bromide group). Each group was given the corresponding drug therapy,and the course of the treatment was 4 weeks. The patients' symptoms and signs were recorded and TCM syndrome scores were obtained before and after treatment. Results: The groups A,B,and D had significant reductions in TCM syndrome scores after treatment( all P 0. 01),and group A had a significantly greater reduction than groups B and C( both P 0. 01),but there was no significant difference between group A and group D( P 0. 05). Group A had a significantly better overall outcome than groups B and C( both P 0. 01),but there was no significant difference between group A and group D( P 0. 05). Conclusion: Anchang Decoction has good clinical efficacy in the treatment of the liver depression and spleen deficiency syndrome of IBS- D,suggesting that liver- soothing treatment plays an important role in the treatment of IBS- D.
【Fund】: 广西壮族自治区自然基金资助项目(编号:2012GXNSFAA053099);; 广西壮族自治区科学研究与技术开发计划基金资助项目(编号:桂科攻1298003-7-2)
【CateGory Index】: R259.744
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved