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《Hunan Journal of Traditional Chinese Medicine》 2016-01
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Effect of Jingqi granules on mouse model of low immune function

XU Lin-ben;LI Yong-min;XIAO Juan;LYU Yuan;XIAO Mei-ying;Institute of Chinese Materia Medica,Hunan Academy of Chinese Medicine;  
Objective:To investigate the effect of Jingqi granules on the mouse model of low immune function.Methods:Cyclophosphamide(Cy) and 60 Co were used to establish two mouse models of low immune function.The weights of immune organs,phagocytic activity of peritoneal macrophages,leukocyte count,content of interleukin-2(IL-2) and interferon-γ(IFN-γ),and levels of immunoglobulin A(IgA) and immunoglobulin M(IgM) were measured and used as the indicators of immune function.Results:In the mouse model established by Cy,Jingqi granules significantly increased the weights of the thymus and spleen,leukocyte count,phagocytic activity of macrophage,and content of IL-2 and IFN-γ;in the mouse model of low immune function established by 60 Co,Jingqi granules significantly increased the weights of the thymus and spleen,phagocytic activity of macrophage,and levels of IgA and IgM.Conclusion:Jingqi granules can improve immune function.
【Fund】: 湖南省科技计划资助项目(编号:2014TT2006)
【CateGory Index】: R285.5;R-332
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