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《Hunan Journal of Traditional Chinese Medicine》 2018-02
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Clinical effect of Shenqi Roumai mixture in treatment of patients with coronary heart disease complicated by carotid atherosclerotic plaque: an analysis of 50 cases

SONG Zhi-hui;NIU Yan-yun;HU Cui-ping;WANG Yong;KANG Hua;Handan Hospital of Traditional Chinese Medicine;  
Objective: To investigate the clinical effect of Shenqi Roumai mixture in the treatment of patients with coronary heart disease complicated by carotid atherosclerotic plaque. Methods: A total of 100 patients with coronary heart disease complicated by carotid atherosclerotic plaque who met the inclusion criteria were randomly divided into control group and treatment group,with 50 patients in each group. The patients in the control group were given conventional Western medicine treatment,and those in the treatment group were given Shenqi Roumai mixture in addition to the conventional Western medicine treatment. The two groups were compared in terms of the changes in carotid color Doppler ultrasound indices,blood lipids,and inflammatory factors. Results: Both groups had significant reductions in carotid intima-media thickness and plaque area after treatment(P 0. 05),while there were no significant differences between the two groups(P 0. 05). Both groups had significant improvements in blood lipids and inflammatory factors after treatment(P 0. 05),and the treatment group had significantly greater improvements than the control group(P 0. 01). Both groups had a significant change in plaque Crouse score after treatment,and there was a significant difference in plaque Crouse score between the two groups(P 0. 05 or P 0. 01). Conclusion:In patients with coronary heart disease complicated by carotid atherosclerotic plaque,Shenqi Roumai mixture combined with Western medicine treatment can effectively improve and delay the progression of plaques and exert a marked therapeutic effect on carotid intima-media thickness,plaques,blood lipids,and inflammatory factors.
【Fund】: 河北省科技厅资助项目(编号:162777111D);; 河北省中医药管理局资助项目(编号:2015274)
【CateGory Index】: R259
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