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《Chemistry》 2008-06
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Preliminary Study on the Molecularly Imprinted Polymer of Bovine Hemoglobin

Yu Shuang,Wang Lei,Geng Lina,Sun Liquan,Luo Aiqin~*,Deng Yulin~*(School of Life Science and Technology,Beijing Institute of Technology,Beijing 100081)  
The molecularly imprinted polymer(MIP) for bovine hemoglobin(BHb) had been synthesized by the hydrogel imprinting technology,in which acrylamide was chosen as monomer and N,N'-methylene bisacrylamide as crosslinker.The preparation conditions were optimized by investigating the effect of the concentrations of the monomer and crosslinker on the adsorption properties.The adsorption binding experiment was carried out to investigate the selectivity of the MIP.It was clearly demonstrated that the MIPs prepared were BHb-specific.Scanning electron microscope(SEM) analysis of the polymer was also taken to characterize the surface morphology of the MIPs.It was shown that the surface of gel beads had a large quantity of macropores,which were helpful to discriminate the protein template.The results showed that the method established owns potential promises.
【Fund】: 北京理工大学基础研究基金项目(20070642008 20070642009)资助
【CateGory Index】: O631.3
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 SUN Rui-feng, LUO Hui, YU Hui-min, SHEN Zhong-yao (Department of Chemical Engineering, Tsinghua University, Beijing 100084, China);Preparation and Specific Molecular Recognition Properties of Human Hemoglobin Imprinted Polymers[J];The Chinese Journal of Process Engineering;2005-03
【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 QIN Hong1,HAN Jian-zhong2 (1.Changshu Institute of Technology, Changshu 215500, China; 2.Department of Food Quality and Safety, Zhejiang Gongshang University, Hangzhou 310035, China);Progress of Proteins Imprinted Technique and Prospect of Its Application[J];Food Science;2007-08
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【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 GUO Hong Sheng, HE Xi Wen , DENG Chang Hui, LI Yi Jun (Department of Chemstry, The Key Lab of Functional Polymer Materials for Adsorption and Separation, Nankai University, Tianjin 300071, China);Studies of Selective Enrichment and Recognized Characteristics of Paracetamol Molecular Template Polymer[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;2000-03
2 Sui Hongyan, Li Hongqi, Shen Zhongyao (Department of Chemical Engineering, Tsinghua University,Beijing 100084);Molecular Imprinting Technique──A New Affinity Separation Method[J];CHEMICAL INDUSTRY AND ENGINEERING PROGRESS;2000-05
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