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《West China Journal of Pharmaceutical Sciences》 2005-04
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Synthesis and characterization of molecularly imprinted polymer of Cefathiamidine

HUANG Zhao-fa, TANG You-wen~(*) (Department of Chemistry, South China Normal University, Guangzhou 510631, China)  
OBJECTIVE To synthesize a molecular imprinting polymer selective for Cefathiamidine. METHODS Different monomers and porogens were investigated and the binding characteristics of the template polymer were evaluated.RESULTS The polymer taking 4-vinylpyridine (4-VP) as an interacting monomer and toluene as a porogen exhibits high affinity to the substrate, Cefathiamidine. CONCLUSION Molecularly imprinted polymer can be used in solid phase extraction and represent clinical utility for enrichment and determination of trace Cefathiamidine.
【Fund】: 广东省自然科学基金资助(批准号:31503)
【CateGory Index】: TQ463.53
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