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《Journal of Harbin Medical University》 2007-04
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Effects of resveratrol on the adhesion,motility and invasion of human mucoepidermoid carcinoma cell line MEC-1 in vitro

GUO Yang,ZHENG Ying-ai,XIE Xiao-hua (Department of Othodontics,The Second Clinical College,Harbin Medical University,Harbin 150081,China)  
Objective To investigate the effects of resveratrol(Res) on the adhesion,motility,and invasion of human mucoepidermoid carcinoma cell line MEC1 in vitro.Methods The adhesion ability of MEC-1 cells was investigated with MTT colorimetric assay.The motility and invasion of MEC-1 cells were assayed by biopore membrane Millicell-PCF inserts culture system.Results The adhesion of MEC-1 cells treated with 100μmol/L Res for 1h or 2h reduced by 23.42% and 34.31%(P0.05),respectively.The motility and invasion of MEC-1 cells treated with 100μmol/L Res reduced by 47.92% and 47.25%(P0.05),respectively.Conclusion Res has an anti-invasion effect on human mucoepidermoid carcinoma cells in vitro,so it may be a potential antineoplastic against tumor invasion or a kind of chemopreventive agent.
【CateGory Index】: R739.8
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 LI Yun-Chuan, JI Wen-Yue Department of Otorhinolaryngology, First Hospital, China Medical University, Shenyang 110001, China;Priliminary investigation on resveratrol in inhibiting growth of laryngeal carcinoma Hep-2 cells in vitro[J];Journal of The Fourth Military Medical University;2005-09
【Co-citations】
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1 LI Yan et al(Key Lab of West Biology Recourses and Modern Biotechnology,Education Ministry,College of Life Science of Northwest University,Xian,Shaanxi 710069);Research Progress on the Pharmacological Effects and Synthesis Pathway of Resveratrol[J];Journal of Anhui Agricultural Sciences;2009-11
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3 WEN Tao ZENG Yang YU Xiao CHENG Shi-ming LI Zhuo-xi YANG Wen-yu(Agronomy College,Sichuan Agricultural University,Ya'an,Sichuan 625014);EFFECT OF FUNGAL ELICITORS ON SYNTHESIZE OF RESVERATROL IN Polygonum cuspidatum CALLUS[J];Journal of Nuclear Agricultural Sciences;2008-04
4 REN Yi-jun,GE Chang-zheng,GAO Feng-xi The Affiliated Jingzhou Hospital,Tongji Medical College of Central China Technology University,Jingzhou,Hunan,China,434020;Progress in the Treatment of Cancer of Larynx With Chinese Herbs[J];Guiding Journal of Traditional Chinese Medicine and Pharmacy;2009-07
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6 TAN Zhi-Yuan, ZHOU Guo-Hai, LIU Sheng-Kai, CHEN Xue-Xiang, GONG Zhu-Qiong, CAO Yong (Northwest Forestry Planning & Designing Institute, Xi'an 710048, Shanxi, China;Hunan Province Key Laboratory of Forest Product and Chenical Industry Engineering, Jishou University, Zhangjiajie 427000, Hunan, China);Effects of Habitat Conditions on the Content of Resveratrol in Polygonum cuspidatum[J];Nonwood Forest Research;2006-01
7 LIU Bin, WU Jun-zheng, SITU Zhen-qiang. (Deptartment of Oral Biology, College of Stomatology, Fourth Military Medical University, Xi'an 710032, China);Effects of the Exogenous PTEN Tumor Suppressor Gene on Adhesion, Migration and Invasion of the Highly Metastatic Mucoepidermoid Carcinoma Cell Line[J];Stomatology;2004-02
8 CAO Yong~(1,2), YU Hua-zhong~2, ZHANG Min~2, LI Guo-zhang~2, XIAO Lang-tao~1ture University, Industry Engineering, Jishou University,Zhangjiajie 427000,China);HPLC DETERMINATION OF RESVERATROL CONTENT IN POLYGONUM CUSPIDATUM AND THE STABILITY OF RESVERATROL[J];Chemistry & Industry of Forest Products;2004-02
9 LEI Yong1,CAO Yong1,CHEN Xue-xiang2,LI Wei3(1.College of Food Science,South China Agriculture University,Guangzhou 510642,China;2.College of Bioscience and Biotechnology,Hunan Agriculture University,Changsha 410128,China;3.College of Biology and Environmental Science,Jishou University,Jishou 416000,China);Determination of Resveratrol Content in Different Parts and Calluses of Polygonum cuspidtums Sieb. et Zucc. by HPLC[J];Chemistry and Industry of Forest Products;2007-S1
【Secondary Citations】
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1 YU Liang, SUN Zhong Ji, WU Sheng Li, PAN Cheng En Department of Hepatobiliary Surgery, First Hospital of Xi'an Jiaotong University, Xi'an 710061, China;Effect of resveratrol on cell cycle proteins in murine transplantable liver cancer[J];Journal of The Fourth Military Medical University;2002-23
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