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《Journal of Harbin Medical University》 2007-04
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Relationship between serum interferon-inducible protein-10 level and disease status in patients with systemic lupus erythematosus

WANG Jing-lu,YU Hui-min,WANG Zhen-yu (Department of Traditional Chinese Medicine,The Second Clinical College,Harbin Medical University,Harbin 150081,China)  
Objective To explore the relationship between serum interferon-inducible protien-10(IP-10) level and disease status in patients with systemic lupus erythematosus(SLE).Methods Using ELISA to detect IP-10 level in serum of 86 active stage patients,59 paracmasia patients and 31 healthy controls.The relationship between anti-ds-DNA antibody,complement C3,C4 and serum IP-10 level were analyzed.Results IP-10 levels in active SLE patients were obviously higher than that in paracmasia patients and healthy control(P0.05).Serum IP-10 level had positive correlation with anti-ds-DNA antibody(r=0.441,P=0.00085).However,there was no relationship between complement C3,C4 and IP-10 level(r=0.141,P=0.0714;r=0.123,P=0.0546).Conclusion SLE patients' serum IP-10 level can reflect disease active degree.
【Fund】: 黑龙江省卫生厅资助项目(2005-296)
【CateGory Index】: R593.241
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【References】
Chinese Journal Full-text Database 1 Hits
1 LIU Jing,DENG Dan-qi(Department of Dermatology/Rheumatology,the Second Affiliated Hospital of Kunming Medical College, Kunming ,China);The relationship of chemokines and systemic lupus erythematosus[J];Journal of Dermatology and Venereology;2009-01
【Co-references】
Chinese Journal Full-text Database 4 Hits
1 MA Yue1,LI Xiao-lan1,DU Gui-zhen2,XU Guo-li3(1.Department of Clinical Laboratory,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China;2.Department of Clinical Laboratory,the Lingyuan No.1 People's Hospital,Lingyuan 122500,China;3.Department of Clinical Laboratory,the Affiliated Zhongshan Hospital of Dalian University,Dalian 116001,China);Changes in serum level of IL-6,IL-8 in active patiets with systemic lupus erythematosus and its clinic value[J];Journal of Dalian Medical University;2007-05
2 LIANG Ming,LI Youji,YANG Xiao,Xu Hanshi,GUAN Weiming,CHEN Weiying,LI Zhijian.Department of Nephrology,First Affiliated Hospital,Sun Yat Sen University of Medical Science,Guangzhou 510080,China;Expression of chemokine RANTES in renal tissue of lupus nephritis[J];Chinese Journal of Rheumatology;2002-03
3 WANG Jianyou, ZHENG Min, YAN Jianliang, LIU Lunfei, CHEN Jisu. Department of Dermatology and Venereology, The Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou 310009, China;Serum Levels of Chemokines in the Patients With Systemic Lupus Erythematosus[J];Chinese Journal of Dermatology;2002-01
4 LIU Zhong juan *,LIN Jia you,NI An ping,SONG Yao hong,SHEN Ying,ZHANG Shi min *Department of Laboratory Medicine, Peking Union Medical College Hospital, CAMS and PUMC, Beijing 100730, China;Serum levels of IFN-Inducible protein-10 relating to the activity of systemic lupus erythematosus[J];Chinese Journal of Laboratory Medicine;2005-01
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 SONG Xin-ying;MA Bing;WANG Xiao-ming;Department of Radiology,Shengjing Hospital,China Medical University;;Meta-analysis on Monocyte Chemoattractant Protein-1 Promoter-2518 A/G Polymorphism and Lupus Nephritis[J];Chinese General Practice;2014-10
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