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《Journal of Harbin Medical University》 2012-01
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Anti-neurosyphilis combined with glucocorticoids for sero-fixation of patients with late syphilis

MAO Zu-hao,ZHOU Xian-yi,WU Zhong,HAN Xue,HU Yan-qing,LU Yan(Department of Dermatology,The Third Affiliated Hospital of Southern Medical University,Guangzhou 510630,China)  
Objective To evaluate the efficacy,safety,and the time of the TRUST titer fast descending with the medicine of anti-neuosyphilitic agents and glucocorticoid in treatment of patients with late syphilis.Methods Sero-fixation of patients with late syphilis were randomly divided into A and B groups.C group made up of patients with syphilis in first teatment.There were 7,10 and 9 cases in A,B and C groups.The patients of the A group were treated with the medicine of anti-neurosyphilis and glucocorticoids.The ones of the B and the C groups were treated with benzithine penicillin.Results There were all TRUST titer descending in 7 cases of A group and 10 cases of C group after treatment,while nobody of TRUST titer descending in B group.There was significant difference between A and B groups(P0.01),but no significant difference between A and C groups(P0.05).It spent(15.14±5.58) days and(66.63±33.12) days of TRUST titer descending in A and C groups,and it was significant difference(P0.01).Conclusion The TRUST titer can be fast descended with the medicine of antineurosyphilis and glucocorticoids in treatment of patients with late syphilis.
【Fund】: 广东省科技计划项目(2011B031800224)
【CateGory Index】: R759.13
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