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《Journal of Harbin Medical University》 2012-01
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Effect of ligustrazin on exercise tolerance of patients with pulmonary fibrosis

GE Dong-jie,BAO Yong-xia,WANG Jing,SUN Bing,ZHENG Hui(Department of Respiratory Diseases,The Second Affiliated Hospital of Harbin Medical University,Harbin 150081,China)  
Objective To explore the exercise capacity and life quality of patients with pulmonary fibrosis treated by ligustrazin.Methods Sixty patients with pulmonary fibrosis were divided into 2 groups : ligustrazin group and hydrocortisone group.Treatment lasted 2 months and efficacy was compared.Results After 2 months,not only lung function and blood gas were evidently raised(P0.05),but also the maximal work、VO2max/kg、VO2/HR、VEmax were obviously improved(P0.05) in ligustrazin group.Conclusion Ligustrazin can improve the exercise cardiopulmonary capacity and life quality of patients with pulmonary fibrosis.
【Fund】: 黑龙江省教育厅课题基金资助(11521097)
【CateGory Index】: R563.9
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