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《Orthopaedics》 2012-01
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Clinically diagnostic value of SPECT bone imaging combined with ESR and CRP for ankylosing spondylitis

LIU Yun,ZHAO Ming.Department of Nuclear Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China  
Objective To approach the diagnostic value of the SPECT bone imaging in combination with ESR and CRP for ankylosing spondylitis.Methods Fifteen patients with ankylosing spondylitis underwent 99mTc-MDP whole body bone imaging.All patients received X-ray examination or computed tomography scan.ESR,and serum CRP and RF were determined.Results Fourteen patients were positive for the bone imaging,accounting for 93.3%.The total scores from the bone imaging were correlated with ESR and CRP with the correlation coefficients being 0.8497 and 0.9545 respectively,but not with RF.The density of joints which is damaged by whole body bone imaging had a linear correlation with ESR and CRP,but not with RF.Conclusion 99mTc-MDP whole body bone imaging combined with ESR and CRP may be used to estimate bone invasion and the metabolism of the diseased bone in ankylosing spondylitis.
【CateGory Index】: R593.23
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