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Qixiang Wang* and Fei Wei Department of Chemical Engineering, Tsinghua University, Beijing 100084, P. R. China *Author to whom correspondence should be addressed. Tel: 0086-10-62784468, E-mail: wangqixiang@tsinghua.org.cn  
The research of nanoscale process engineering (NPE) is based on the interdisciplinary nature of nano-scale science and technology. It mainly deals with transformation of materials and energy into nanostructured materials and nanodevices, and synergizes the multidisciplinary convergence between materials science and technology, bio-technology, and information technology. The core technologies of NPE concern all aspects of nanodevice construction and operation, such as manufacture of nanomaterials by design? concepts and design of nanoarchitectures, and manufacture and control of customizable nanodevices. Two main targets of NPE at present are focused on nanoscale manufacture and concept design of nanodevices. The research progress of nanoscale manufacturing processes focused on creating nanostructures and assembling them into nanosystems and larger scale architectures has built the interdis-cipline of NPE. The concepts and design of smart, multi-functional, environmentally compatible and customizable nan-odevice prototypes built from the nanostructured systems of nanocrystalline, nanoporous and microemulsion systems are most challenging tasks of NPE. The development of NPE may also impel us to consider the curriculum and educa-tional reform of chemical engineering in universities.
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