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《Basic & Clinical Medicine》 2009-07
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Genetic polymorphisms of seventeen Y-chromosomeal STR loci in Heiyi Zhuang ethnic group in Guangxi province

TENG Shao-kang1*,CAO Lin-zhi2,HUANG Shi-ning1,HUANG Chang-sheng1(1.Dept.of Anatomy;2.Dept.of Biochemistry,Youjiang Medical College for Nationalities,Baise 533000,China)  
Objective To investigate the Allelic and haplotype frequency distribution of seventeen short tandem repeat loci of Y chromosome in Heiyi Zhuang ethnic groups in Guangxi province.Methods Seventeen Y-STR loci,of which the template DNAs were extracted from blood samples of 184 unrelated male individuals in Heiyi Zhuang population,were amplified by using the AmpFlSTR YfilerTM.The PCR products were genotyped with ABI PRISM 310 genetic analyzer.Results The Gene diversity ranged from 0.4910 to 0.9727 at DYS456、DYS389Ⅰ、DYS390、DYS389Ⅱ、DYS458、DYS19、DYS385a\b、DYS393、DYS391、DYS439、DYS635、DYS392、Y-GATA-H4、DYS437、DYS438、DYS448.A total of 180 different haplotypes were observed,The haplotype diversity value calculated from all 17 loci was 0.99976.The significant difference of the allelic frequency distribution in Y-STR loci was found between Heiyi Zhuang population and other observed populations.Conclusion The 17th Y-STR loci in Heiyi Zhuang population of Guangxi province are highly affluent genetic polymorphic and can offer valuable genetic datas for paternity testing and paternal genetic lineages evolution.
【Fund】: 广西科学基金(桂科青0640075)
【CateGory Index】: Q987
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