Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Basic & Clinical Medicine》 2009-07
Add to Favorite Get Latest Update

Regulatory mechanisms of PTEN

HONG Jun-bo,LU·· Nong-hua*(Department of Gastroenterology,the First Affiliated Hospital,Medical College of NanChang University,Nanchang 330006,China)  
PTEN(Phosphatase and Tensin Homology deleted from Chromosome ten),a putative antioncogene,encodes a PTEN protein that has a dual specificity phosphatase activity with both protein phosphatase and lipid phosphatase,which regulates a variety of molecules through inhibiting the PI3K/Akt signaling pathway.Recently,some scholars dedicate to the modulation of PTEN,which demonstrates that PTEN can be regulated by multiple factors at the level of gene and protein.This review briefly summarizes up-to-date information about the modulation of PTEN and its mechanisms.
【Fund】: 江西省自然基金(0540070)
【CateGory Index】: R730.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Lin Yang Li-Ge Kuang Hua-Chuan Zheng Jin-Yi Li Dong-Ying Wu Su-Min Zhang Yan Xin No.4 Lab,Cancer Institute,The First Affiliated Hospital,China Medical University,Shenyang 110001,China Ying Chen Shen Yang Gynecology & Obstetrics Hospital,Shenyang 110014,China;PTEN encoding product:a marker for tumorigenesis and progression of gastric carcinoma[J];世界胃肠病学杂志(英文版);2003-01
2 Sun Hongwei2,Zheng Huachuan1,Yang Xuefei1,Wu Dongying1,Zhang Sumin1,Kuang Lige1,and Xin Yan1*1The Fourth Laboratory, Cancer Institute, the First Affiliated Hospital ofChina Medical University, Shenyang 1100012Department of Internal Medicine, Liaoning Tumor Hospital, Shenyang 110042;EXPRESSION OF PTEN AND CASPASE-3 AND THEIR CLINICOPATHOLOGICAL SIGNIFICANCE IN PRIMARY GASTRIC MALIGNANT LYMPHOMA[J];中国医学科学杂志(英文版);2004-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHAO Hongchun WANG Yanfei PU Zhangjie CHE Juan Department of Otorhinolaryngology,Affiliated Hospital of Binzhou Medical University,Binzhou 256603;Relation between expression of PTEN protein in human laryngeal carcinoma and its biological characteristic[J];Journal of Binzhou Medical University;2011-04
2 Zhao Mei-zhong,Ying Wei-hong The Fourth Municipal People's Hospital of Wenling,Wenling(317511),China;Relationship Between the PTEN Protein Expression Deletion and Differentiation Grades in Patients with Gastric Cancer[J];Journal of Radioimmunology;2010-01
3 WANG Guiqiang CHEN Gai WEI Maohua YANG Shengquan Intensive Care Unit,People's Hospital of Luzhou City,Luzhou 646000,China;Expression and significance of PTEN in human gastric carcinoma[J];China Medicine and Pharmacy;2012-16
4 Lu Qiang1,Zang Aimin1,Feng Shuming2(1.Department of Pathology,Affiliated Hospital of Hebei University,Baoding,Hebei 071000,China; 2.Department of Internal Medicine,Maternal and Child Health Hospital of Xushui County,Baoding,Hebei 072550,China);Express and significance of PTEN and P27~(kip1) in gastric carcinoma and precancerous lesions[J];Chongqing Medicine;2013-05
5 ZHANG Li-gong;JIA Jian-guang;JIN Xin;XIE Bo;CHENG Ze-nong;QIAN Jun;Department of Surgery Oncology,The First Affiliated Hospital of Bengbu Medical College;Department of Pathology,The First Affiliated Hospital of Bengbu Medical College;;The expression of PTEN and P-AKT in gastric carcinoma and its significance[J];Journal of Bengbu Medical College;2014-03
6 ZHAO Hong-wei1,2, LI Long-jiang2, PAN Jian2, HAN Bo2, WEN Yu-ming2. (1. Key. Laboratory of Oral Biomedical Engineering of Ministry of Education, Sichuan University, Chengdu 610041, China; 2. Dept. of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China);Effect on induction of differentiation of Tca8113 cells affected by abscisic acid in vitro[J];West China Journal of Stomatology;2007-05
7 ZHANG Chunxu,CHEN Yongchun,XU Aiguo.(The Affiliated Hospital to Medical School of Ningbo University,Ningbo 315020,Zhejiang,China);Expression of PTEN and Her-2 protein in gastric cancer and its clinical significance[J];Modern Practical Medicine;2011-09
8 YE Xiao-feng,GAO Ping,HAN En-shan,et al.(The Affiliated Hospital of Ningxia Medical University,Yinchuan 750004,China);Expression of MMP-2 and PTEN in esophageal squamous cell carcinoma and their clinical significance[J];Ningxia Medical Journal;2010-11
9 Wang Jianzheng,Feng Xiaoshan,Zhou Fuyou,Gao Shegan,Wang Xinshuai,Yang Haijun,Wang Qiayin(Department of Oncology Surgery,the First Affiliated Hospital of Henan University of Science and Technology, Henan University of Science and Technology Institute of Tumor,Luoyang 471003,China);Expressions of EGFR and PTEN in Esophageal Carcinoma Tissues[J];Journal of Basic and Clinical Oncology;2013-02
10 LI Da-yong,et al.(Department of General Surgery,the Second People's Hospital,Wuhu,Anhui 241000,the P.R.China);Expression and significance of PCNA and PTEN in patients with gastric cancer[J];Journal of Qiqihar University of Medicine;2012-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 SUN Yong-qiao~(1,2) LIU Qing-you~(1,2) (1.Graduate School of the Chinese Academy of Sciences,Bei fing 10004912.Beijing Institute of Genomics of chinese Academy of Scienes,Beijing 101300);Progress on Bovine Genome Project[J];China Cattle Science;2007-02
2 SUN Manji~(1,2) LU Dexun~(2*) WANG Lifang~2 LI Ran~1 (1.Northeast Agricultural University,Harbin 150030,China;2.Inner Mongolia Agricultural University,Huhhot 010018,China);Study on Nutrient Uptake and Utilization in the Mammary Gland of Guanzhong Dairy Goats Fed Basal Diet[J];Chinese Journal of Animal Nutrition;2009-06
3 QI Lizhi YAN Sumei SHENG Ran AO Changjin(College of Animal Science,Inner Mongolia Agricultural University,Huhhot 010018,China);Effects of Milk Component Precursors on Milk Composition Synthesis in the Mammary Gland of Dairy Cows:a Review[J];Chinese Journal of Animal Nutrition;2011-12
4 TIAN Tian,ZHAI Hong-rui,CHEN Yu-zhen,LIU Ruo-yu(College of Animal Science,Guizhou University,Guizhou Key Laboratory of Animal Genetics Breeding and Reproduction,Guiyang,Guizhou 550025,China);Cloning of Bovine β-Casein Gene and Its Sequential Analysis[J];Guizhou Agricultural Sciences;2009-08
5 WANG Zhi-guo,BU Deng-pan,WANG Jia-qi(Institute of Livestock Veterinary,Chinese Academy of Agriculture Science,The Key Lab of Animal Nutrition,Beijing 100094,China);Bovine Mammary Epithelial Cells Beta-Casein Protein Detection and Karyotype Analysis[J];China Animal Husbandry & Veterinary Medicine;2007-02
6 WU Juan, WANG Feng-long, WANG Shen-yuanDepartment of Pathology, College of Animal Science and Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018;Primary Culture of Bovine Mammary Epithelial Cells[J];农业科学与技术(英文版);2009-01
7 CHEN Zhong-Min1) ,HU Ying-Chun1),MO Lin2),HUO Yan-Ying1),XU Qin-Zhi1),ZHOU Ping-Kun1),WU De-Chang1)(1) Beijing Institute of Radiation Medicine,Beijing 100850,China;2) Chongqing Medical University,Chongqing 400016,China);PTEN Upregulates Rad51 Gene Expression Through the Inhibition of PI3K-AKT Signal Pathway[J];Chinese Journal of Biochemistry and Molecular Biology;2011-03
8 SUN Xiao-xu,LIN Ye,GAO Xue-jun,LI Qing-zhang(Key laboratory of dairy science ministry of education,Northeast Agricultural University,Harbin 150030,China);Research progress of glucose regulates the lactose bio-synthesis of the lactation progress in the mammary gland[J];China Dairy Industry;2013-05
9 CUI Li-li~(1,2),BU Deng-pan~1,WANG Jia-qi~1,LUO Shu-ping~2 (1.State Key Laboratory of Animal Nutrition,Institute of Animal Science,CAAS,Beijing 100094,China;2.College of Agronomy,Xinjiang Agricultural University,Urumqi Xinjiang 830052,China);Establishment of Bovine Mammary Epithelial Cell Culture System[J];Xinjiang Agricultural Sciences;2006-05
10 LI Xiang-chen~1, REN Fang-li~(1,2), ZHANG Yong~1(1.College of Animal Science and Technology, Northwest Sci-Tech University of Agriculture andForestry,Yangling 712100,China; 2. Institute of Biomedicine,Tsinghua University,Beijing 100084,China);Establishment and Ultrastructural Characterization of Goat Mammary Epithelial Cell Line[J];Chinese Journal of Animal and Veterinary Sciences;2005-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved